[接受血液透析的慢性肾功能不全患者的下丘脑-垂体-性腺轴]
[Hypothalamo-hypophyseo-gonadal axis in individuals with chronic renal insufficiency subjected to hemodialysis].
作者信息
Mendoza C, Carreras A, Ruiz E, Ortega E, Hervás J, Osorio C
出版信息
Rev Esp Fisiol. 1985 Dec;41(4):443-6.
The role of pituitary and sexual hormones in 21 patients with chronic renal failure (CRF) and related impotence and loss of libido who were being treated by hemodialysis and in 15 normal male controls has been studied. In both groups the serum levels of FSH, LH and TSH, PRL before and after injection of both LHRH and TRH were measured as well as the basal levels of Testosterone (T) and Estradiol (E2). The results show similar values for testosterone in both groups and statistically significant higher basal values for FSH, LH, TSH and PRL and lower basal values for E2 in CRF patients.
研究了垂体激素和性激素在21例接受血液透析治疗的慢性肾衰竭（CRF）患者及相关阳痿和性欲减退患者，以及15名正常男性对照者中的作用。在两组中，均测量了注射促性腺激素释放激素（LHRH）和促甲状腺激素释放激素（TRH）前后的促卵泡生成素（FSH）、促黄体生成素（LH）、促甲状腺激素（TSH）、催乳素（PRL）的血清水平，以及睾酮（T）和雌二醇（E2）的基础水平。结果显示，两组中的睾酮值相似，CRF患者中FSH、LH、TSH和PRL的基础值在统计学上显著更高，而E2的基础值更低。
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