Chaix A F, Allal J, Gallimard J F, Petitalot J P, Bouin-Pineau M H, Barraine R, Rousseau G
Arch Mal Coeur Vaiss. 1985 Oct;78(10):1486-92.
A prospective study of carotid artery atheroma by vascular echotomography and spectral analysis was performed in 40 patients with myocardial infarction and 40 control subjects. Carotid artery atheroma was commoner in the group of patients with myocardial infarction (72.5% +/- 6.8%), earlier (9 years), more commonly bilateral (37.5% +/- 7.6%) and more stenotic (32.5% +/- 7.4%) than in the control group (p less than 0.000a, p less than 0.0001 and p less than 0.002, respectively). The severity of carotid artery atheroma correlated with the site of coronary artery disease; the following significant relationships were found: stenosing 40% and/or bilateral carotid atherosclerosis and left anterior descending disease (p less than 0.02); carotid atherosclerosis and double or triple vessel disease (p less than 0.05). The authors conclude that detection of carotid artery atheroma after myocardial infarction is valuable for two reasons: it gives an indication as to the severity of the coronary disease; carotid endarterectomy may be considered at the same time as coronary artery bypass surgery.
对40例心肌梗死患者和40例对照者进行了一项通过血管超声断层扫描和频谱分析对颈动脉粥样硬化的前瞻性研究。心肌梗死组患者的颈动脉粥样硬化更为常见(72.5%±6.8%),发病更早(9年),双侧病变更常见(37.5%±7.6%),狭窄程度更高(32.5%±7.4%),均高于对照组(分别为p<0.000a、p<0.0001和p<0.002)。颈动脉粥样硬化的严重程度与冠状动脉疾病的部位相关;发现以下显著关系:狭窄40%及/或双侧颈动脉粥样硬化与左前降支病变(p<0.02);颈动脉粥样硬化与双支或三支血管病变(p<0.05)。作者得出结论,心肌梗死后检测颈动脉粥样硬化有两个价值:它可提示冠状动脉疾病的严重程度;在进行冠状动脉搭桥手术的同时可考虑行颈动脉内膜切除术。