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印度新生儿颅内脑室尺寸的列线图和参考范围

Nomograms and Reference Ranges for Intra-Cranial Ventricular Dimensions in Indian Neonates.

作者信息

Khare Ayush, Gaur Ajay Kumar, Mittal Megha, Bansal Satvik Chaitanya

机构信息

Department of Pediatrics, Gajra Raja Medical College, Gwalior, Madhya Pradesh, 474012, India.

Department of Radiodiagnosis, Gajra Raja Medical College, Gwalior, Madhya Pradesh, 474012, India.

出版信息

Indian J Pediatr. 2024 Oct 9. doi: 10.1007/s12098-024-05274-z.

DOI:10.1007/s12098-024-05274-z
PMID:39382772
Abstract

OBJECTIVES

To establish normal reference values for commonly used ventricular indices - Anterior Horn Width (AHW), Ventricular Index (VI) and Thalamo-Occipital Distance (TOD)-against common variables including gestational age, birth weight and head circumference in Indian newborns.

METHODS

This was a cross-sectional study. Cranial ultrasound was performed between post-natal days 3 to 7. Anterior fontanelle was taken as the acoustic window. Data were analyzed to determine correlation, coefficient of determination (R2), regression equations and plotted against gestational age (GA).

RESULTS

Total 2200 newborns were included in the study. The study observed that there is an increase in VI, AHW and TOD with an increase in gestational age (p-value < 0.001) and birth weight (p-value < 0.001). No significant correlation of gender and singleton or multiple gestation-with the intraventricular dimensions was observed (p-value > 0.05). All the three ventricular parameters were found to have a significantly lower mean value in the normal vaginal delivery group as compared to the LSCS group. There was a good correlation between ventricular indices of the left and right side. Nomograms of AHW, TOD, and VI were prepared with respect to gestational age.

CONCLUSIONS

Intracranial ventricular size dimensions vary significantly with increasing gestational age and birth weight. The new nomograms for various ventricular indices of Indian neonates can assist in objectively assessing ventricular sizes.

摘要

目的

针对印度新生儿,建立常用脑室指数——前角宽度(AHW)、脑室指数(VI)和丘脑枕距(TOD)——与包括胎龄、出生体重和头围在内的常见变量的正常参考值。

方法

这是一项横断面研究。在出生后第3至7天进行颅脑超声检查。以前囟为声窗。分析数据以确定相关性、决定系数(R2)、回归方程,并与胎龄(GA)作图。

结果

该研究共纳入2200例新生儿。研究观察到,随着胎龄(p值<0.001)和出生体重(p值<0.001)的增加,VI、AHW和TOD也增加。未观察到性别以及单胎或多胎妊娠与脑室内尺寸有显著相关性(p值>0.05)。与剖宫产组相比,正常阴道分娩组的所有三个脑室参数的平均值均显著较低。左右侧脑室指数之间存在良好的相关性。根据胎龄绘制了AHW、TOD和VI的列线图。

结论

颅内脑室大小随胎龄和出生体重的增加而显著变化。印度新生儿各种脑室指数的新列线图有助于客观评估脑室大小。

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Childs Nerv Syst. 2024 Mar;40(3):673-684. doi: 10.1007/s00381-023-06176-9. Epub 2023 Oct 9.
2
Analysis of cranial ultrasound images for newborn.新生儿颅脑超声图像分析
Front Neurol. 2023 Jan 4;13:1090275. doi: 10.3389/fneur.2022.1090275. eCollection 2022.
3
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4
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5
Consensus Approach for Standardizing the Screening and Classification of Preterm Brain Injury Diagnosed With Cranial Ultrasound: A Canadian Perspective.颅超声诊断早产脑损伤的筛查与分类标准化的共识方法:加拿大视角
Front Pediatr. 2021 Mar 8;9:618236. doi: 10.3389/fped.2021.618236. eCollection 2021.
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