State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection & Key Lab of Biopesticide and Chemical Biology, Ministry of Education, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P. R. China.
College of Resources and Environment, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P. R. China.
J Agric Food Chem. 2024 Oct 23;72(42):23160-23172. doi: 10.1021/acs.jafc.4c06096. Epub 2024 Oct 9.
-induced potato late blight is considered the "cancer of the potato crop." In this work, mesoporous silica nanoparticles (MSNs) with ultrahigh specific surface area (786.28 m/g) were synthesized, which significantly inhibited compared with some commercial fungicides. Moreover, MSNs inhibited the growth and reproductive of processes, including germination, sporangia infection, and zoospore release. MSNs targeted key biological pathways and induced a stress response in the , leading to reactive oxygen species (•O, •OH, and O) production and structural damage of sporangia. Pot experiments showed that MSNs are translocated from leaves to roots of potato plants, enhancing physiological and biochemical processes, alleviating drought stress, improving resistance to pathogens, and exhibiting soil microbe-friendly. This study systematically reveals the mechanism of MSNs to weaken the reproduction process of and confirm the safety and feasibility of MSNs as a green and sustainable fungicide.
诱导的马铃薯晚疫病被认为是“马铃薯作物的癌症”。在这项工作中，合成了具有超高比表面积（786.28 m/g）的介孔硅纳米颗粒（MSNs），与一些商业杀菌剂相比，它显著抑制了马铃薯晚疫病的生长和繁殖。此外，MSNs 抑制了 的生长和繁殖过程，包括萌发、孢子囊感染和游动孢子释放。MSNs 靶向关键的生物途径，并在 中诱导应激反应，导致活性氧（•O、•OH 和 O）的产生和孢子囊的结构损伤。盆栽实验表明，MSNs 从马铃薯植株的叶片转移到根部，增强了生理生化过程，缓解了干旱胁迫，提高了对病原体的抗性，并表现出对土壤微生物的友好性。本研究系统地揭示了 MSNs 削弱 的繁殖过程的机制，并证实了 MSNs 作为一种绿色可持续杀菌剂的安全性和可行性。
