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超声引导腹横肌平面阻滞作为一种有效途径,可减少腹腔镜减重手术后阿片类药物的消耗:一项随机对照试验的系统评价和荟萃分析。

Ultrasound-Guided Transversus Abdominis Plane Block as an Effective Path to Reduce Opioid Consumption After Laparoscopic Bariatric Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

机构信息

Beth Israel Deaconess Medical Center, Boston, USA.

Spaulding Rehabilitation Hospital, Boston, USA.

出版信息

Obes Surg. 2024 Nov;34(11):4244-4254. doi: 10.1007/s11695-024-07532-7. Epub 2024 Oct 10.

Abstract

Effective postoperative pain management is essential to the patient's recovery. The use of opioids as the primary line of pain treatment has been known to increase rates of length of stay, pulmonary complications, paralytic ileus, and nausea and vomiting. Therefore, guidelines strongly recommend alternative paths to reduce opioid consumption through multimodal analgesia, and the transversus abdominis plane block(USG-TAP) has been considered to be one of these optimistic alternatives. A comprehensive systematic search was conducted in four databases until April 2024. We only considered for this analysis randomized controlled trials that assessed the USG-TAP as part of multimodal anesthesia in patients undergoing laparoscopic bariatric surgery. Eleven studies comprising 789 patients were included in the meta-analysis. Our results showed a significant decrease in opioid consumption after the first 24 h of surgery (MD - 32.02 mg; 95% IC - 51.33, - 12.71; p < 0.01) and fewer patients required extra-dose of opioid (OR 0.20; 95% IC 0.07, 0.62; p < 0.01). The pain score showed to be also improved with the TAP block (MD - 0.69; 95% IC - 1.32, - 0.07; p = 0.03). No difference concerning time to deambulate, nausea and vomiting, and time of surgery was observed among the studies. This study reinforces the benefits of the use of USG-TAP block as part of multimodal analgesia in patients undergoing laparoscopic bariatric surgery.

摘要

有效的术后疼痛管理对于患者的康复至关重要。众所周知,使用阿片类药物作为主要的疼痛治疗方法会增加住院时间、肺部并发症、麻痹性肠梗阻、恶心和呕吐的发生率。因此,指南强烈建议通过多模式镇痛来寻找替代途径来减少阿片类药物的使用,而经腹横肌平面阻滞(USG-TAP)已被认为是这些乐观替代方案之一。我们在四个数据库中进行了全面的系统搜索,直到 2024 年 4 月。我们仅考虑了评估 USG-TAP 作为腹腔镜减肥手术患者多模式麻醉一部分的随机对照试验进行此分析。共有 11 项研究,包含 789 名患者纳入荟萃分析。我们的结果表明,手术后 24 小时内阿片类药物的消耗量显著减少(MD -32.02mg;95%CI -51.33,-12.71;p <0.01),需要额外阿片类药物剂量的患者更少(OR 0.20;95%CI 0.07,0.62;p <0.01)。TAP 阻滞也显示出疼痛评分的改善(MD -0.69;95%CI -1.32,-0.07;p =0.03)。各研究之间在开始行走的时间、恶心和呕吐以及手术时间方面无差异。这项研究强调了在腹腔镜减肥手术患者中使用 USG-TAP 阻滞作为多模式镇痛一部分的益处。

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