Department of Obstetrics and Gynecology, School of Medicine, Teikyo University, 2-11-1, Kaga, Itabashi-ku, Tokyo, 173-8606, Japan.
Sci Rep. 2024 Oct 9;14(1):23539. doi: 10.1038/s41598-024-70279-9.
To investigate whether assisted reproductive technology (ART) affects gross fetal movement. A prospective cohort study. 65 women who conceived with ART (ART group) and 211 women (control group) without ART recorded fetal movement with the fetal movement acceleration measurement recorder at night weekly after 28 weeks. The number ratio of 10 s epochs with fetal movement to all epochs was calculated as the fetal movement parameter. When no fetal movement was observed for more than 5 min, it was defined as a no fetal movement period, and the average number per hour, the average duration, and the longest duration of the no fetal movement periods were calculated as the no fetal movement parameters. Gestational weeks were classified into 28-33 and 34-39 weeks, and the fetal movement parameter and the no fetal movement parameters were compared using the Student's t-test. The fetal movement parameters at 28-33 weeks were 17.43% (ART) and 16.58% (control) (p = 0.219), and those at 34-39 weeks were 11.72% (ART) and 11.96% (control) (p = 0.590). In the same way, for the no fetal movement parameters, the average numbers were 1.58 and 1.63 per hour (p = 0.357), and 2.36 and 2.30 per hour (p = 0.503). The average durations were 8.30 and 8.46 min (p = 0.712), and 9.20 and 9.51 min (p = 0.188). The longest durations were 16.26 and 17.02 min (p = 0.295), and 22.34 and 22.87 min (p = 0.534). ART does not affect gross fetal movement count.
探讨辅助生殖技术（ART）是否会影响胎儿的总体运动。一项前瞻性队列研究。65 名通过 ART 受孕的妇女（ART 组）和 211 名未接受 ART 的妇女（对照组）在 28 周后每周夜间使用胎儿运动加速测量记录器记录胎儿运动。将 10 s 有胎动的时相较所有时相的比值计算为胎动参数。当连续 5 min 无胎动时，定义为无胎动期，计算每小时平均胎动数、平均持续时间和最长持续时间。将孕周分为 28-33 周和 34-39 周，采用 Student's t 检验比较两组的胎动参数和无胎动参数。28-33 周时，ART 组的胎动参数为 17.43%（ART）和 16.58%（对照组）（p=0.219），34-39 周时，ART 组的胎动参数为 11.72%（ART）和 11.96%（对照组）（p=0.590）。同样，对于无胎动参数，每小时的平均值分别为 1.58 次和 1.63 次（p=0.357），2.36 次和 2.30 次（p=0.503）。平均持续时间分别为 8.30 分钟和 8.46 分钟（p=0.712），9.20 分钟和 9.51 分钟（p=0.188）。最长持续时间分别为 16.26 分钟和 17.02 分钟（p=0.295），22.34 分钟和 22.87 分钟（p=0.534）。ART 并不影响胎儿的总体运动计数。
