Teo Vanessa H Y, Chia Kai Li, Bowen Catherine, Lahiri Manjari, Cheung Peter P M, Turner Deborah E, Carter Kate
School of Health Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, SO17 1BJ, UK.
Division of Rheumatology, Department of Medicine, National University Hospital, Singapore, 119074, Singapore.
BMC Rheumatol. 2024 Oct 9;8(1):52. doi: 10.1186/s41927-024-00409-3.
Psoriatic Arthritis (PsA)-related foot involvement has been shown to have a profound impact on daily functioning, with most studies having focused on predominantly Caucasian populations. The aim was to describe disabling foot pain (DFP) and its impact on daily living in PsA in Singapore.
A cross-sectional, retrospective study was conducted using clinical data collected during a single-visit to a rheumatology clinic in Singapore. Records for adults with physician-diagnosed PsA were reviewed for sociodemographic information, disease characteristics, global disease activity and burden. Foot-specific measures included clinical assessment and the Manchester Foot Pain and Disability Index used to define DFP and evaluate between-group differences.
Forty-two participants with PsA (83% female, 57% Chinese, 31% Malay, 9.5% Indian, mean (SD) age 54-years (16)) attended the rheumatology clinic over the study-period. The median (IQR) disease duration was 2-years (11) and all were taking current DMARDs. Global disease measures demonstrated mild-to-moderate global disease activity and mild functional impairment, and were significantly higher in those with DFP. Despite 90% reporting to be coping well with their condition, self-care and having emotional support (n = 38), this study sample demonstrated high levels of anxiety/depression (29%), sleep disturbance (34%) and fatigue (24%), and a lack of disease- and drug-specific knowledge (64%). Further management was indicated for medication adherence counselling (48%), occupational therapy (43%), physiotherapy (36%) and podiatry (30%). Nearly half had current foot pain with 40% reporting DFP (n = 17), which caused significantly greater difficulty walking 3 km than those without DFP (p < 0.05). Rearfoot enthesitis (plantar fasciitis, Achilles enthesitis) was the most common cause of DFP (67%) with pain lasting longer than 1-year. 72% were overweight or obese, with a high proportion not engaging in any cardiovascular exercise (70%). Three of 42 participants had previously seen a podiatrist.
People with DFP in PsA experience more severe global disease activity, reduced mobility and higher levels of negative impact on their daily lives in Singapore. In the absence of working in a multidisciplinary-team, there is value in comprehensive assessments that have potential to capture a holistic view of personal impact and improve person-centred care in PsA.
银屑病关节炎(PsA)相关的足部受累已被证明对日常功能有深远影响,大多数研究主要集中在白种人群体。目的是描述新加坡PsA患者的致残性足部疼痛(DFP)及其对日常生活的影响。
采用在新加坡一家风湿病诊所单次就诊时收集的临床数据进行横断面回顾性研究。对成年医师诊断为PsA的患者记录进行审查,以获取社会人口统计学信息、疾病特征、整体疾病活动度和负担情况。足部特异性测量包括临床评估以及用于定义DFP和评估组间差异的曼彻斯特足部疼痛与残疾指数。
在研究期间,42名PsA患者(83%为女性,57%为华裔,31%为马来裔,9.5%为印度裔,平均(标准差)年龄54岁(16岁))到风湿病诊所就诊。疾病持续时间的中位数(四分位间距)为2年(11年),所有患者均正在服用当前的改善病情抗风湿药物(DMARDs)。整体疾病测量显示整体疾病活动度为轻度至中度,功能损害为轻度,且在有DFP的患者中显著更高。尽管90%的患者报告其病情得到良好控制、有自我护理且有情感支持(n = 38),但该研究样本显示焦虑/抑郁水平较高(29%)、睡眠障碍(34%)和疲劳(24%),并且缺乏疾病和药物相关知识(64%)。对于药物依从性咨询(48%)、职业治疗(43%)、物理治疗(36%)和足病治疗(30%),需要进一步管理。近一半患者目前有足部疼痛,40%报告有DFP(n = 17),与无DFP的患者相比,这导致行走3公里时困难显著更大(p < 0.05)。后足附着点炎(足底筋膜炎、跟腱附着点炎)是DFP最常见的原因(67%),疼痛持续超过1年。72%的患者超重或肥胖,很大一部分人未进行任何心血管运动(70%)。42名参与者中有3人之前看过足病医生。
在新加坡,PsA伴DFP的患者经历更严重的整体疾病活动度、行动能力下降以及对其日常生活的负面影响水平更高。在缺乏多学科团队协作的情况下,进行全面评估具有价值,这种评估有可能全面了解个人所受影响,并改善PsA的以患者为中心的护理。