Fear, learning, and the amygdala: a personal reflection in honor of Joseph LeDoux.

In honor of Joseph LeDoux's retirement from an illustrious career in science, I offer a personal reflection on how my graduate training experiences in his lab shaped my subsequent career trajectory and the development of my views on human amygdala function and the scientific enterprise. I discuss the values of openness to scientific exploration and of multi-methodological integration, both of which distinguished his laboratory over the years. I highlight the unique historical context in which the lab's foundational discoveries on the emotional brain occurred and the importance of embracing new technologies to advance an understanding of brain-behavior relationships in affective neuroscience.