Smith Austin, Yeoh Cindy, Massengill Christopher, Yang Wendy, Mahil Amreesh
Department of Anesthesiology, Moffitt Cancer Center, Tampa, USA.
Morsani College of Medicine, University of South Florida Morsani College of Medicine, Tampa, USA.
Cureus. 2024 Sep 9;16(9):e69009. doi: 10.7759/cureus.69009. eCollection 2024 Sep.
Limb-girdle muscular dystrophy (LGMD) presents a unique challenge for anesthesiologists because of the potential complications related to surgery and anesthesia. This is a case of a 55-year-old male with colon cancer and a history of LGMD, who underwent a low anterior resection colectomy under general anesthesia. Because of the pathogenic variants in the RYR1 gene implicated in various congenital myopathies, we review clinical concerns associated with LGMD and describe the anesthetic management of our patient with LGMD and a potentially difficult airway.
肢带型肌营养不良症（LGMD）给麻醉医生带来了独特的挑战，因为存在与手术和麻醉相关的潜在并发症。这是一例55岁男性结肠癌患者，有LGMD病史，在全身麻醉下接受了低位前切除术结肠切除术。由于RYR1基因的致病变异与多种先天性肌病有关，我们回顾了与LGMD相关的临床问题，并描述了对这位患有LGMD且气道可能困难的患者的麻醉管理。
