Suppr超能文献

甲下棘层松解性角化不良性棘皮瘤:1例报告及文献复习

Subungual Acantholytic Dyskeratotic Acanthoma: A Case Report and Literature Review.

作者信息

Gupta Ankit, de Menezes Sara Lee, Howard Matthew David, O'Keefe Rod, Prakash Saurabh, Kern Johannes Steffen

机构信息

Royal Australian College of General Practitioners, East Melbourne, VIC, Australia.

Skin Health Institute, Carlton, VIC, Australia.

出版信息

Skin Appendage Disord. 2024 Oct;10(5):433-438. doi: 10.1159/000538624. Epub 2024 May 16.

Abstract

INTRODUCTION

Subungual acantholytic dyskeratotic acanthoma is a rare benign tumor of epidermal keratinocytes characterized by acantholysis and dyskeratosis. Only 7 other cases have been published in the literature.

CASE PRESENTATION

A 29-year-old male presented with painful erythronychia and onycholysis of the left thumbnail. He worked as an electrician and was ambidextrous. Two months prior to the onset, he reported completing a mechanical task which led to repeated and sustained pressure to his left thumb. The clinical diagnosis was onychopapilloma, and a longitudinal excision was performed to remove the tumor. However, on histopathological examination, the primary features were hyperkeratosis, acantholysis, and dyskeratosis, consistent with a final diagnosis of subungual acantholytic dyskeratotic acanthoma.

CONCLUSION

Nail trauma was reported by our case as a preceding feature, and this has not been described previously. Pain may accompany nail changes in the presentation of this tumor. Although subungual acantholytic dyskeratotic acanthoma is a benign tumor, it caused disruption in productivity, and our case highlights the need for timely access to specialist nail services.

摘要

引言

甲下棘层松解性角化不良性棘皮瘤是一种罕见的表皮角质形成细胞良性肿瘤,其特征为棘层松解和角化不良。文献中仅报道过其他7例病例。

病例报告

一名29岁男性,左拇指出现疼痛性甲下红斑和甲分离。他是一名电工,双手灵巧。发病前两个月,他报告完成了一项机械任务,导致左手拇指反复持续受压。临床诊断为甲乳头瘤,并进行了纵向切除以切除肿瘤。然而,组织病理学检查显示,主要特征为角化过度、棘层松解和角化不良,最终诊断为甲下棘层松解性角化不良性棘皮瘤。

结论

我们的病例报告指甲外伤为先前特征,此前未曾有过描述。该肿瘤表现时,疼痛可能伴随指甲变化。虽然甲下棘层松解性角化不良性棘皮瘤是一种良性肿瘤,但它会影响工作效率,我们的病例强调了及时获得专业指甲服务的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d942/11460838/0109999916b6/sad-2024-0010-0005-538624_F01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验