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外用伊维菌素治疗头皮酒渣鼻。

Scalp Rosacea Treated with Topical Ivermectin.

作者信息

Dall'Oglio Federica, Nasca Maria Rita, Guglielmi Giulia, Micali Giuseppe

机构信息

Dermatology Clinic, University of Catania, Catania, Italy.

出版信息

Skin Appendage Disord. 2024 Oct;10(5):429-432. doi: 10.1159/000537807. Epub 2024 May 15.

Abstract

INTRODUCTION

Scalp rosacea is often misdiagnosed or overlooked, and few reports deal with this peculiar localization. Furthermore, the pharmacological approach to scalp rosacea remains a therapeutic challenge, as no topical and/or systemic drugs have been approved for this specific area so far.

CASE PRESENTATION

A series of 5 adult patients affected by inflammatory rosacea and concurrent scalp involvement, confirmed by dermoscopy and histopathology with negative microbiologic swabs, and effectively treated with ivermectin 1% cream once daily for 12 weeks is presented.

CONCLUSION

Our experience, although limited, suggests that evaluation of rosacea subjects should also include the scalp and that the treatment with ivermectin 1% cream may be effective on scalp rosacea.

摘要

引言

头皮酒渣鼻常被误诊或忽视,很少有报告涉及这一特殊部位。此外,头皮酒渣鼻的药物治疗方法仍然是一个治疗挑战,因为目前尚无局部和/或全身药物被批准用于这一特定区域。

病例报告

本文介绍了5例成年患者,经皮肤镜和组织病理学检查确诊为炎性酒渣鼻且伴有头皮受累,微生物拭子检查为阴性,每天外用1%伊维菌素乳膏治疗,持续12周,治疗效果良好。

结论

我们的经验虽然有限,但表明酒渣鼻患者的评估也应包括头皮,且1%伊维菌素乳膏治疗头皮酒渣鼻可能有效。

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本文引用的文献

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Advances in pharmacotherapy for rosacea: what is the current state of the art?玫瑰痤疮治疗的药理学进展:目前的最新技术是什么?
Expert Opin Pharmacother. 2022 Nov;23(16):1845-1854. doi: 10.1080/14656566.2022.2142907. Epub 2022 Nov 5.
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Emerging topical drugs for the treatment of rosacea.治疗酒渣鼻的新兴局部用药物。
Expert Opin Emerg Drugs. 2021 Mar;26(1):27-38. doi: 10.1080/14728214.2021.1887138. Epub 2021 Feb 18.
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Alternative uses of dermoscopy in daily clinical practice: An update.皮肤镜在日常临床实践中的其他用途:更新。
J Am Acad Dermatol. 2018 Dec;79(6):1117-1132.e1. doi: 10.1016/j.jaad.2018.06.021. Epub 2018 Jun 18.
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Ivermectin 1% (CD5024) for the treatment of rosacea.伊维菌素 1%(CD5024)治疗酒渣鼻。
Expert Opin Pharmacother. 2018 Apr;19(5):511-516. doi: 10.1080/14656566.2018.1447562. Epub 2018 Mar 16.
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Medical Management of Facial Redness in Rosacea.酒渣鼻面部发红的医学处理。
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Indian J Dermatol Venereol Leprol. 2015 Sep-Oct;81(5):511-3. doi: 10.4103/0378-6323.162340.
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Ivermectin: A Review in Rosacea.伊维菌素:酒渣鼻治疗的研究进展。
Am J Clin Dermatol. 2015 Oct;16(5):447-52. doi: 10.1007/s40257-015-0150-8.
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Treatment of extrafacial rosacea with low-dose isotretinoin.低剂量异维A酸治疗面部外酒渣鼻
Acta Derm Venereol. 2010 Jul;90(4):409-10. doi: 10.2340/00015555-0888.
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Rosacea with extensive extrafacial lesions.伴有广泛面部外皮损的酒渣鼻。
Int J Dermatol. 2008 Jan;47(1):52-5. doi: 10.1111/j.1365-4632.2007.03360.x.

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