Saha Chanchal, Haque Farzana, Islam Nazrul, Hossain Muhammad Minoar, Easin Arafat Md, Yousuf Mohammad Abu, Rahman Mohammad Motiur
Department of Computer Science and Engineering, Mawlana Bhashani Science and Technology University, Tangail-1902, Bangladesh.
Institute of Information Technology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh.
Heliyon. 2024 Sep 23;10(19):e38175. doi: 10.1016/j.heliyon.2024.e38175. eCollection 2024 Oct 15.
Plasmonic sensors utilizing surface plasmon resonance (SPR) have emerged as powerful tools for sensitive and label-free detection across a wide range of applications. This study introduces a new dual-core silver-coated plasmonic sensor designed to significantly enhance sensitivity and resolution, making it particularly effective for precise analyte detection in complex environments. A key innovation of this sensor lies in its dual-core architecture, which achieves the highest wavelength sensitivity reported at 30,000 nm/RIU and resolution of RIU, covering a broad refractive index (RI) range from 1.34 to 1.41. Furthermore, the integration of machine learning (ML) algorithms, including multiple-variable linear regression (MLR), support vector regression (SVR), and random forest regression (RFR), marks a significant advancement in sensor design. These algorithms enable dynamic adaptation and the extraction of data-driven insights, enhancing the sensor's performance in predicting confinement loss and wavelength across various analytes. The innovative combination of a dual-core design and ML integration positions this plasmonic sensor as a highly sensitive and versatile tool well-suited for advanced bio-sensing applications.
利用表面等离子体共振(SPR)的等离子体传感器已成为广泛应用中用于灵敏且无标记检测的强大工具。本研究介绍了一种新型的双核镀银等离子体传感器,该传感器旨在显著提高灵敏度和分辨率,使其在复杂环境中进行精确分析物检测时特别有效。该传感器的一项关键创新在于其双核架构,它实现了所报道的最高波长灵敏度,为30,000 nm/RIU,分辨率为 RIU,覆盖从1.34到1.41的宽折射率(RI)范围。此外,机器学习(ML)算法的集成,包括多元线性回归(MLR)、支持向量回归(SVR)和随机森林回归(RFR),标志着传感器设计的重大进步。这些算法能够实现动态自适应并提取数据驱动的见解,提高传感器在预测各种分析物的限制损耗和波长方面的性能。双核设计与ML集成的创新组合使这种等离子体传感器成为一种高度灵敏且通用的工具,非常适合先进的生物传感应用。