Strakosha Ariana, Pasko Nevi, Cadri Vilma, Rista Elvana, Aliu Dorina, Arapi Blerim
Department of Nephrology, University Hospital Center "Mother Theresa", Tirana, Albania.
Department of Nephrology, Hygeia Hospital Tirana, Tirana, Albania.
Radiol Case Rep. 2024 Sep 25;19(12):6385-6389. doi: 10.1016/j.radcr.2024.08.142. eCollection 2024 Dec.
Chronic kidney disease (CKD) is a complex medical condition that extends beyond the progressive decline in renal function. It is associated with mineral and bone disorders, notably secondary hyperparathyroidism due to dysregulated calcium and phosphate metabolism. However, distinguishing between secondary and primary hyperparathyroidism can be challenging. We report the case of a 74-year-old male with CKD, who presented with elevated serum levels of parathyroid hormone (PTH), CKD, and unexplained hypercalcemia, despite management for secondary hyperparathyroidism. Advanced imaging techniques revealed a primary parathyroid adenoma, subsequently confirmed by histopathology. The successful surgical resection of the adenoma resulted in the calcium and PTH levels falling into a normal range, highlighting the need for a careful differential diagnosis in CKD patients.
慢性肾脏病（CKD）是一种复杂的医学病症，其影响超出了肾功能的渐进性下降。它与矿物质和骨代谢紊乱相关，尤其是由于钙和磷代谢失调导致的继发性甲状旁腺功能亢进。然而，区分继发性和原发性甲状旁腺功能亢进可能具有挑战性。我们报告了一例74岁患有CKD的男性病例，尽管对其继发性甲状旁腺功能亢进进行了治疗，但他仍出现甲状旁腺激素（PTH）血清水平升高、CKD以及不明原因的高钙血症。先进的成像技术显示存在原发性甲状旁腺腺瘤，随后经组织病理学证实。腺瘤的成功手术切除使钙和PTH水平降至正常范围，凸显了对CKD患者进行仔细鉴别诊断的必要性。
