影响使用高生物利用度口服抗生素疗法治疗人工关节感染的因素。
Factors influencing the use of highly bioavailable oral antibiotic therapy for the treatment of prosthetic joint infections.
作者信息
Granger Marie-Félixe, Leis Jerome A, Hempel Amanda, Pincus Daniel, Ravi Bheeshma, Daneman Nick, Lam Philip W
机构信息
Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Division of Infectious Diseases, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
出版信息
Infect Control Hosp Epidemiol. 2024 Oct 10;45(11):1-4. doi: 10.1017/ice.2024.159.
Abstract
We conducted a retrospective cohort study to identify factors influencing intravenous (IV) versus oral antibiotic therapy in first-episode prosthetic joint infections. Of the 34/78 (44%) cases treated intravenously, negative cultures (26%), concomitant infections necessitating IV antibiotics (21%), and delays in susceptibility testing (15%) were the most common reasons for IV therapy.
摘要
我们进行了一项回顾性队列研究，以确定影响首次人工关节感染时静脉注射与口服抗生素治疗的因素。在34例（占78例中的44%）接受静脉注射治疗的病例中，培养结果为阴性（26%）、伴有需要静脉注射抗生素的感染（21%）以及药敏试验延迟（15%）是静脉注射治疗最常见的原因。
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