门诊肠外抗菌治疗中经外周插入的中心静脉导管堵塞的预测因素。
Predictors of Peripherally Inserted Central Catheter Occlusion in the Outpatient Parenteral Antimicrobial Therapy Setting.
机构信息
Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Trillium Health Partners, Mississauga, Ontario, Canada.
出版信息
Antimicrob Agents Chemother. 2018 Aug 27;62(9). doi: 10.1128/AAC.00900-18. Print 2018 Sep.
Abstract
In this retrospective study of 285 patients receiving outpatient parenteral antibiotic therapy (OPAT), the duration of antibiotic, use of double-lumen catheters, and receipt of penicillin G and cloxacillin appeared to increase the risk of peripherally inserted central catheter (PICC) occlusion. Physicians should consider these factors when prescribing long-term antibiotic therapy. Further studies are needed to evaluate methods to reduce PICC occlusion, particularly when double-lumen PICCs are necessary and when cloxacillin or penicillin G are the preferred treatment.
摘要
在这项对 285 名接受门诊肠外抗生素治疗 (OPAT) 的患者进行的回顾性研究中，抗生素使用时间、双腔导管使用以及青霉素 G 和氯唑西林的使用似乎增加了经外周中心静脉置管 (PICC) 堵塞的风险。医生在开长期抗生素治疗时应考虑这些因素。需要进一步研究以评估减少 PICC 堵塞的方法，特别是在需要使用双腔 PICC 且首选治疗药物为氯唑西林或青霉素 G 时。
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