Li Jiawen, Wu Zhibin, Luo Fang, Lin Zhenyu, Wang Jian, Li Rui, Qiu Bin
Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Eel farming and processing, Fuzhou University, Fuzhou, Fujian 350108, P. R. China.
Department of Dermatology, Fuzhou First General Hospital, Fuzhou, Fujian 350009, China.
Anal Chem. 2024 Oct 22;96(42):16783-16792. doi: 10.1021/acs.analchem.4c03392. Epub 2024 Oct 10.
Lead halide perovskites have garnered attention as promising electrochemiluminescence (ECL) emitters owing to their superior photophysical characteristics. However, their poor water stability severely restricts their application in aqueous media for ECL. In this study, inorganic perovskite CsPbBr was assembled in situ in the imine-linked covalent-organic framework (COF-LZU1) as a novel ECL emitter. The expansive surface area and robust hydrophobic architecture of COF-LZU1 not only improved the water stability of CsPbBr but also guaranteed its exceptional ECL performance. The novel composite nanoluminescent material was coated onto an indium tin oxide (ITO) electrode via spin-coating and calcination processes to serve as an electrochemiluminescence (ECL) platform. A sensor was developed by combining a DNA hydrogel target-induced release system with a platform using ascorbic acid (AA) as a coreactant and T-2 toxin as the target analyte model. This method achieved a detection limit as low as 3.56 fg·mL and was successfully applied to the analysis of the T-2 toxin content in corn samples. This study offers a novel path for the advancement of perovskite-based ECL emitters and their utilization in aqueous environments within the ECL field.
卤化铅钙钛矿因其优异的光物理特性而作为有前景的电化学发光（ECL）发光体受到关注。然而，它们较差的水稳定性严重限制了其在ECL水性介质中的应用。在本研究中，无机钙钛矿CsPbBr原位组装在亚胺连接的共价有机框架（COF-LZU1）中作为新型ECL发光体。COF-LZU1的大表面积和坚固的疏水结构不仅提高了CsPbBr的水稳定性，还保证了其优异的ECL性能。通过旋涂和煅烧工艺将新型复合纳米发光材料涂覆在氧化铟锡（ITO）电极上，用作电化学发光（ECL）平台。通过将DNA水凝胶靶标诱导释放系统与以抗坏血酸（AA）为共反应剂、T-2毒素为靶标分析物模型的平台相结合，开发了一种传感器。该方法实现了低至3.56 fg·mL的检测限，并成功应用于玉米样品中T-2毒素含量的分析。本研究为基于钙钛矿的ECL发光体的发展及其在ECL领域水性环境中的应用提供了一条新途径。
