基于区域的现有全基因组关联研究分析确定了新的潜在胶质瘤遗传易感区域。
Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma.
机构信息
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Australia.
Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
出版信息
Cancer Res Commun. 2024 Nov 1;4(11):2933-2946. doi: 10.1158/2767-9764.CRC-24-0385.
Abstract
Further investigation of the potential susceptibility regions identified in our study may lead to a better understanding of glioma genetic risk and the underlying biological etiology of glioma. Our study suggests sex may play a role in genetic susceptibility and highlights the importance of sex-specific analysis in future glioma research.
摘要
进一步研究我们研究中确定的潜在易感区域可能有助于更好地理解胶质母细胞瘤的遗传风险和潜在的生物学病因。我们的研究表明，性别可能在遗传易感性中起作用，并强调了在未来的胶质母细胞瘤研究中进行性别特异性分析的重要性。
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