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在一家退伍军人事务医疗中心接受初次或翻修全膝关节置换术的患者中,研究区域麻醉使用、阿片类药物处方和疼痛评分的差异:一项回顾性队列研究。

Examining Disparities in Regional Anesthesia Utilization, Opioid Prescriptions, and Pain Scores Among Patients Who Received Primary or Revision Total Knee Arthroplasty at a Veterans Affairs Medical Center: A Retrospective Cohort Study.

作者信息

Bennett Samuel, Woodbury Anna, Udoji Mercy

机构信息

Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA 30322, USA.

Department of Anesthesiology, Atlanta Veterans Affairs Medical Center, Decatur, GA 30033, USA.

出版信息

Mil Med. 2025 Feb 27;190(3-4):e736-e743. doi: 10.1093/milmed/usae463.

DOI:10.1093/milmed/usae463
PMID:39388317
Abstract

INTRODUCTION

Total knee arthroplasty (TKA) is one of the most performed surgical operations in the United States. Managing postoperative pain after TKA is of vital importance, as it is positively associated with outcome measures related to recovery of function and quality of life. Two commonly used methods to control postoperative pain are regional anesthesia (RA), consisting of a single or a combination of peripheral nerve and epidural blocks, and pain medication, such as opioids. Our retrospective analysis sought to better understand whether revision versus primary TKA impacted previously discovered disparities in perioperative pain management and use of RA at the Atlanta Veterans Affairs Health Care System (AVAHCS). Before data collection, we hypothesized that revision TKA would have a higher proportion of Black and older patients and that revision TKA patients would have lower postoperative pain scores.

MATERIALS AND METHODS

This was a retrospective analysis of AVAHCS patients who underwent elective unilateral primary or revision TKA surgery between 2014 and 2020. After application of our exclusion criteria, data from 562 patients were analyzed. Data collected included demographics information, type of RA used, and pain scores. Statistical analyses included chi-square test, t-tests, multiple logistic regression, and multiple linear regression, as appropriate to the outcomes of interest.

RESULTS

Revision TKA patients were more likely to be Black (P = .018) and younger (P = .023 for <50 years of age group, P = .006 for 50 to 64 years of age compared to the >65 years group). Black patients, compared to White patients, had significantly higher pain scores at baseline (P = .0086) and at 24 hours postsurgery (P = .0037). Older patients (≥50 years old) had significantly higher baseline pain scores (P = .021 for the 50 to 64 years group, P < .01 for the >65 years group) and significantly lower first postanesthesia care unit pain scores (P < .05). Black race (P < .01) and age > 65 years (P < .01) were associated with a significant decrease in total oral morphine equivalents (OME) prescribed at discharge. None of the predictor variables-race, age, type of surgery (primary versus revision), baseline, and first postanesthesia care unit pain scores-were significantly associated with the use of RA in our cohort.

CONCLUSIONS

Sociodemographic disparities in pain management have been reported in all healthcare systems, including the VAHCS. This moderately sized retrospective study, conducted at a single veterans affairs site, yielded several noteworthy findings. One finding of particular interest was that, despite Black patients reporting higher baseline and 24-hour postoperative pain scores, they were prescribed fewer opioids at discharge. Our results highlight the presence of clinically significant disparities in perioperative TKA pain management, emphasizing the need for continuous investigation and focused mitigation efforts among Veterans.

摘要

引言

全膝关节置换术(TKA)是美国开展最为频繁的外科手术之一。TKA术后疼痛管理至关重要,因为它与功能恢复和生活质量相关的预后指标呈正相关。两种常用的控制术后疼痛的方法是区域麻醉(RA),包括单种或多种外周神经阻滞和硬膜外阻滞的联合应用,以及使用阿片类等止痛药物。我们的回顾性分析旨在更好地了解翻修TKA与初次TKA相比,是否会影响此前在亚特兰大退伍军人事务医疗保健系统(AVAHCS)中发现的围手术期疼痛管理和RA使用方面的差异。在数据收集之前,我们假设翻修TKA的患者中黑人和老年患者的比例会更高,并且翻修TKA患者的术后疼痛评分会更低。

材料与方法

这是一项对2014年至2020年间在AVAHCS接受择期单侧初次或翻修TKA手术患者的回顾性分析。应用我们的排除标准后,对562例患者的数据进行了分析。收集的数据包括人口统计学信息、所使用的RA类型和疼痛评分。根据感兴趣的结果,统计分析包括卡方检验、t检验、多元逻辑回归和多元线性回归。

结果

翻修TKA患者更可能是黑人(P = 0.018)且更年轻(年龄<50岁组P = 0.023,50至64岁组与>65岁组相比P = 0.006)。与白人患者相比,黑人患者在基线时(P = 0.0086)和术后24小时(P = 0.0037)的疼痛评分显著更高。老年患者(≥50岁)的基线疼痛评分显著更高(50至64岁组P = 0.021,>65岁组P < 0.01),且麻醉后护理单元首次疼痛评分显著更低(P < 0.05)。黑人种族(P < 0.01)和年龄>65岁(P < 0.01)与出院时开具的口服吗啡总当量(OME)显著减少相关。在我们的队列中,种族、年龄、手术类型(初次与翻修)、基线和麻醉后护理单元首次疼痛评分等预测变量均与RA的使用无显著关联。

结论

在包括VAHCS在内的所有医疗保健系统中,均报告了疼痛管理方面的社会人口统计学差异。这项在单一退伍军人事务站点进行的中等规模回顾性研究得出了几个值得注意的发现。一个特别有趣的发现是,尽管黑人患者报告的基线和术后24小时疼痛评分更高,但他们出院时开具的阿片类药物却更少。我们的结果突出了围手术期TKA疼痛管理中存在具有临床意义的差异,强调了对退伍军人进行持续调查和针对性缓解措施的必要性。

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