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在军事冲突持续的情况下,为乌克兰癌症患者建立有效的国际医疗后送计划。

Building an Effective International Medical Evacuation Program for Ukrainian Patients With Cancer Amid Prolonged Military Conflict.

机构信息

Department of Liver, Pancreatic and Peritoneal Carcinomatosis Surgery, Kyiv Regional Cancer Center, Kyiv, Ukraine.

Global Medical Knowledge Alliance, Boston, MA.

出版信息

JCO Glob Oncol. 2024 Oct;10:e2400363. doi: 10.1200/GO-24-00363. Epub 2024 Oct 10.

Abstract

PURPOSE

During military conflicts, the immediate response to a severely disrupted health care system often overlooks the needs of patients with cancer who require continuous specialized care. The full-scale Russian invasion of Ukraine in February 2022 was no exception, leaving many Ukrainian patients without access to essential care.

MATERIALS AND METHODS

We conducted a retrospective cohort study to assess the impact of the MedEvac program, facilitating the transfer of Ukrainian patients with cancer to European Union (EU) institutions for treatment, and to describe its components. Patient data from the Ministry of Health of Ukraine (MOH) database (April 2022-April 2023) were analyzed.

RESULTS

Of 639 applications in the MOH database, 339 (53.1%) had sufficient data for analysis and, of those, 281 (82.9%) were evacuated to EU hospitals. Median age of evacuated patients was 47 (IQR, 38-58) years and most were newly diagnosed (94.0%, n = 264). Predominantly, patients were evacuated for systemic cancer therapy (81.9%, n = 230). Multivariate logistic regression analysis revealed that a good performance status (Eastern Cooperative Oncology Group 0-2) was the most significant factor associated with evacuation (odds ratio [OR], 9.64 [95% CI, 3.08 to 30.23]). Patients with melanoma were more likely to be evacuated, even after adjustment for performance status (OR, 2.56 [95% CI, 1.14 to 5.72]), while patients with head and neck cancer were significantly less so (OR, 0.20 [95% CI, 0.06 to 0.72]).

CONCLUSION

MedEvac program provides a viable model for medical evacuation and management of patients with cancer amid prolonged military conflict, highlighting the importance of international cooperation and setting a precedent for other crisis responses. Continuous evaluation and adaptation are essential to ensure the program's effectiveness and sustainability.

摘要

目的

在军事冲突期间,对严重混乱的医疗保健系统的紧急反应往往忽略了需要持续接受专业护理的癌症患者的需求。2022 年 2 月俄罗斯对乌克兰的全面入侵也不例外,导致许多乌克兰患者无法获得基本护理。

材料和方法

我们进行了一项回顾性队列研究,以评估 MedEvac 计划的影响,该计划促进了将乌克兰癌症患者转移到欧盟(EU)机构接受治疗,并描述了其组成部分。从乌克兰卫生部(MOH)数据库(2022 年 4 月至 2023 年 4 月)分析患者数据。

结果

在 MOH 数据库的 639 份申请中,有 339 份(53.1%)有足够的数据进行分析,其中 281 份(82.9%)被转移到欧盟医院。转移患者的中位年龄为 47 岁(IQR,38-58),大多数为新诊断(94.0%,n=264)。患者主要被转移接受全身癌症治疗(81.9%,n=230)。多变量逻辑回归分析显示,良好的体能状态(东部合作肿瘤学组 0-2)是与转移最相关的最重要因素(优势比[OR],9.64[95%CI,3.08 至 30.23])。即使调整了体能状态,黑色素瘤患者也更有可能被转移(OR,2.56[95%CI,1.14 至 5.72]),而头颈部癌症患者则明显较少(OR,0.20[95%CI,0.06 至 0.72])。

结论

MedEvac 计划为在长期军事冲突期间对癌症患者进行医疗后送和管理提供了可行的模式,凸显了国际合作的重要性,并为其他危机应对树立了先例。持续评估和调整对于确保该计划的有效性和可持续性至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c3/11487997/91fd5bf242d1/go-10-e2400363-g001.jpg

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