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静脉-动脉体外膜肺氧合作为肺移植术后两年急性呼吸衰竭和循环休克患者液体复苏的桥梁。

Veno-arterial extracorporeal membrane oxygenation as bridge for fluid resuscitation in a patient with acute respiratory failure and circulatory shock two years post lung transplantation.

作者信息

Segura Ana, Bobba Christopher, Rackauskas Mindaugas, Gries Cynthia, Emtiazjoo Amir M, Maybauer Marc O

机构信息

Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.

Department of Pulmonary, Critical Care and Sleep Medicine, University of Florida College of Medicine, Gainesville, FL, USA.

出版信息

Perfusion. 2025 Jul;40(5):1287-1290. doi: 10.1177/02676591241290389. Epub 2024 Oct 10.

DOI:10.1177/02676591241290389
PMID:39389096
Abstract

BackgroundThe use of extracorporeal membrane oxygenation (ECMO) continues to evolve and is recognized as an important adjunct as a bridge to recovery or a bridge to transplant. We wanted to share our experience of using veno-arterial (VA) ECMO as an adjunct to lung recovery and an aide for fluid resuscitation.Case descriptionWe present the case of a 77-year-old man with a history of previous single lung transplant who had acute respiratory decompensation and cardiovascular collapse secondary to CMV pneumonia and septic shock. He was cannulated for VA ECMO, treated for CMV pneumonia and resuscitated with 5 L of albumin 5% and antibiotics, within 12 hours of cannulation. He required two days of VA ECMO and was ultimately decannulated and discharged to a rehabilitation facility on hospital day 73.ConclusionThis case emphasizes the challenging clinical scenario of fluid resuscitation in a lung transplant patient. With adequate patient selection, a multidisciplinary team and the use of VA ECMO, success can be achieved.

摘要

背景

体外膜肺氧合(ECMO)的应用不断发展,已被公认为是作为恢复桥梁或移植桥梁的重要辅助手段。我们希望分享我们使用静脉-动脉(VA)ECMO作为肺恢复辅助手段和液体复苏辅助手段的经验。

病例描述

我们报告一例77岁男性病例,该患者有单肺移植史,因巨细胞病毒肺炎和感染性休克继发急性呼吸代偿失调和心血管衰竭。在插管后12小时内,他接受了VA ECMO插管,接受了巨细胞病毒肺炎治疗,并使用5升5%白蛋白和抗生素进行复苏。他需要VA ECMO支持两天,最终在住院第73天拔管并转至康复机构。

结论

该病例强调了肺移植患者液体复苏具有挑战性的临床情况。通过适当的患者选择、多学科团队以及VA ECMO的使用,可以取得成功。

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