Division of Cardiology, Duke University Medical Center, Durham, NC, USA; Duke Clinical Research Institute, Durham, NC, USA.
Division of Cardiology, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
J Card Fail. 2024 Oct;30(10):1355-1366. doi: 10.1016/j.cardfail.2024.06.017.
Our comprehension of atrial mechanics, atrial cardiomyopathy and their clinical implications across various cardiovascular conditions has advanced significantly. Atrial interventions can have differing effects on atrial mechanics. With the rapid increase in the use of atrial interventions, it is crucial for investigators and clinicians to acknowledge the potential adverse effects of these interventions on atrial mechanics that might not be clinically significant at the time of interventions. Recognizing the preclinical stage of atrial maladaptation might enable early interventions before the development of irreversible atrial remodeling and clinical manifestation. We review normal atrial function and mechanics, and atrial cardiomyopathy in select cardiovascular conditions. We also summarize and discuss the current evidence of the impact of various atrial interventions on atrial function and mechanics.
我们对心房力学、心房心肌病及其在各种心血管疾病中的临床意义的理解已经有了显著的进展。心房干预措施对心房力学可能产生不同的影响。随着心房干预措施的迅速增加,研究人员和临床医生必须认识到这些干预措施对心房力学的潜在不利影响,这些影响在干预时可能并不具有临床意义。认识到心房适应性不良的临床前阶段,可能使我们能够在不可逆的心房重构和临床症状出现之前进行早期干预。我们回顾了正常心房功能和力学以及特定心血管疾病中的心房心肌病。我们还总结和讨论了各种心房干预措施对心房功能和力学的影响的现有证据。