2nd Department of Internal Medicine and Cardiology Centre, University of Szeged, Szeged, Hungary.
Curr Cardiol Rev. 2021;17(2):217-229. doi: 10.2174/1573403X16666200721153620.
Atrial fibrillation is the most common supraventricular arrhythmia affecting an increasing proportion of the population in which mainstream therapy, i.e. catheter ablation, provides freedom from arrhythmia in only a limited number of patients. Understanding the mechanism is key in order to find more effective therapies and to improve patient selection. In this review, the structural and electrophysiological changes of the atrial musculature that constitute atrial remodeling in atrial fibrillaton and how risk factors and markers of disease progression can predict catheter ablation outcome will be discussed in detail.
心房颤动是最常见的影响人群比例不断增加的室上性心律失常，主流治疗方法，即导管消融，仅能使有限数量的患者免于心律失常。了解机制是关键，以便找到更有效的治疗方法并改善患者选择。在这篇综述中，将详细讨论构成心房颤动心房重构的心房肌结构和电生理变化，以及危险因素和疾病进展标志物如何预测导管消融的结果。
