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[双侧声带麻痹神经修复技术的现状与发展]

[The current status and development of nerve repair techniques for bilateral vocal cord paralysis].

作者信息

Wei Xianfei, Li Meng, Chen Shicai, Zheng Hongliang

机构信息

Department of Otorhinolaryngology Head and Neck Surgery,the First Affiliated Hospital of Naval Medical University(Changhai Hospital),Shanghai,200433,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Oct;38(10):940-946. doi: 10.13201/j.issn.2096-7993.2024.10.011.

DOI:10.13201/j.issn.2096-7993.2024.10.011
PMID:39390934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11839556/
Abstract

The related research of nerve repair for bilateral vocal cord paralysis(BVCP) can be traced back to a century ago. There is still no standardized surgical therapeutic schedule and the evaluation of curative effect, due to the variability and complexity of laryngeal nerve innervation. Otolaryngologists have been constantly weighing and improving the surgical plan in relieving airway obstruction, maintaining vocal function and reducing cough to protect the normal physiological function of the larynx. Different medical institutions have great differences in the treatment methods. Many studies and literatures were published on the treatment of BVCP, yet have few related works on the application of it's nerve repair technology presently. The research progress of nerve repair technology for BVCP were described, along with its developing trend, aiming to lay the foundation for the future technical exploration and development.

摘要

双侧声带麻痹(BVCP)神经修复的相关研究可追溯到一个世纪前。由于喉神经支配的变异性和复杂性,目前仍没有标准化的手术治疗方案和疗效评估方法。耳鼻喉科医生一直在不断权衡和改进手术方案,以缓解气道阻塞、维持发声功能并减少咳嗽,从而保护喉部的正常生理功能。不同医疗机构的治疗方法存在很大差异。关于BVCP的治疗发表了许多研究和文献,但目前关于其神经修复技术应用的相关工作较少。本文描述了BVCP神经修复技术的研究进展及其发展趋势,旨在为未来的技术探索和发展奠定基础。

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本文引用的文献

1
Bilateral selective laryngeal reinnervation in patients with bilateral vocal cord palsy.双侧声带麻痹患者的双侧选择性喉返神经再支配。
Acta Otorhinolaryngol Ital. 2023 Jun;43(3):189-196. doi: 10.14639/0392-100X-N2395.
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Functional Outcomes Following Delayed Laryngeal Reinnervation Of Patients with Vagal Paralysis After Paraganglioma and Schwannoma Surgery.副神经和迷走神经离断后延迟喉返神经功能重建在副神经节瘤和神经鞘瘤术后患者中的应用效果
J Voice. 2023 Jul;37(4):610-615. doi: 10.1016/j.jvoice.2021.03.021. Epub 2021 May 13.
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[Experts consensus on diagnosis and treatment of vocal fold paralysis].[声带麻痹诊断与治疗专家共识]
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Mar 7;56(3):198-209. doi: 10.3760/cma.j.cn115330-20200924-00765.
4
[Clinical analysis of selective laryngeal reinnervation using upper root of phrenic nerve and hypoglossal nerve branch in the treatment of bilateral vocal fold paralysis].[膈神经上根与舌下神经分支选择性喉再支配术治疗双侧声带麻痹的临床分析]
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Nov 7;55(11):1016-1021. doi: 10.3760/cma.j.cn115330-20200526-00444.
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Bilateral Selective Laryngeal Reinnervation for Bilateral Vocal Fold Paralysis in Children.双侧喉返神经选择性再支配术治疗儿童双侧声带麻痹。
JAMA Otolaryngol Head Neck Surg. 2020 May 1;146(5):401-407. doi: 10.1001/jamaoto.2019.4863.
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Selective reinnervation using phrenic nerve and hypoglossal nerve for bilateral vocal fold paralysis.膈神经和舌下神经选择性再神经支配治疗双侧声带麻痹。
Laryngoscope. 2019 Nov;129(11):2669-2673. doi: 10.1002/lary.27768. Epub 2019 Feb 12.
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[The efficacy of ansa cervicalis anterior root for unilateral recurrent laryngeal nerve injury].颈襻前根治疗单侧喉返神经损伤的疗效
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8
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9
Selective reinnervation for bilateral vocal cord paralysis using the superior laryngeal nerve.使用喉上神经对双侧声带麻痹进行选择性再支配。
Laryngoscope. 2015 Nov;125(11):2547-50. doi: 10.1002/lary.25430. Epub 2015 Jul 7.
10
Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.失神经支配后人喉外展肌中肌球蛋白重链亚型的转变
Eur Arch Otorhinolaryngol. 2015 Oct;272(10):2915-23. doi: 10.1007/s00405-015-3664-z. Epub 2015 Jun 10.