Suppr超能文献

喉返神经松解与重建:单机构经验

Recurrent Laryngeal Nerve Liberations and Reconstructions: A Single Institution Experience.

作者信息

Dzodic Radan, Markovic Ivan, Santrac Nada, Buta Marko, Djurisic Igor, Lukic Silvana

机构信息

School of Medicine, University of Belgrade, Belgrade, Serbia.

Surgical Oncology Clinic, Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000, Belgrade, Serbia.

出版信息

World J Surg. 2016 Mar;40(3):644-51. doi: 10.1007/s00268-015-3305-0.

Abstract

BACKGROUND

Recurrent laryngeal nerve (RLN) palsy rates vary from 0.5 to 10%, even 20% in thyroid cancer surgery. The aim of this paper was to present our experience with RLN liberations and reconstructions after various mechanisms of injury.

METHODS

Patients were treated in our institution from year 2000 to 2015. First group (27 patients) had large benign goiters, locally advanced thyroid/parathyroid carcinomas, or incomplete previous surgery of malignant thyroid disease. Second group (5 patients) had reoperations due to RLN paralysis on laryngoscopy. Liberations and reconstructions of injured RLNs were performed.

RESULTS

Surgical exploration of central compartment enabled identification of the RLN injury mechanism. Liberations were performed in 11 patients, 2 months to 16 years after RLN injury, by removing misplaced ligations. Immediate or delayed (18 months to 23 years) RLN reconstructions were performed in 21 patients, by direct suture or ansa cervicalis-to-RLN anastomosis (ARA). RLN liberation provided complete voice recovery within 3 weeks in all patients. Patients with direct sutures had better phonation 1 month after reconstruction. Improved phonation was observed 2-6 months after ARA in 43% of patients.

CONCLUSIONS

Vocal cords do not regain normal movement once being paralyzed after RLN transection, but they restore tension during phonation by reconstruction. Nerve liberation is a useful method which enables patients with RLN paresis/paralysis a significant improvement in phonation, even complete voice recovery. Reinnervation of vocal cords, using one of the mentioned techniques, should be a standard in thyroid and parathyroid surgery, with aim to improve quality of patient's life.

摘要

背景

喉返神经(RLN)麻痹发生率在0.5%至10%之间,在甲状腺癌手术中甚至可达20%。本文旨在介绍我们在各种损伤机制后进行喉返神经松解和重建的经验。

方法

2000年至2015年在我院治疗的患者。第一组(27例患者)患有巨大良性甲状腺肿、局部晚期甲状腺/甲状旁腺癌或既往恶性甲状腺疾病手术不完整。第二组(5例患者)因喉镜检查发现喉返神经麻痹而进行再次手术。对损伤的喉返神经进行松解和重建。

结果

中央区的手术探查能够确定喉返神经损伤机制。11例患者在喉返神经损伤后2个月至16年进行了松解,通过移除错位结扎。21例患者进行了即刻或延迟(18个月至23年)的喉返神经重建,采用直接缝合或颈袢至喉返神经吻合术(ARA)。喉返神经松解使所有患者在3周内声音完全恢复。直接缝合的患者在重建后1个月发声更好。43%的患者在ARA后2至6个月观察到发声改善。

结论

喉返神经横断后声带一旦麻痹就不会恢复正常运动,但通过重建在发声时可恢复张力。神经松解是一种有用的方法,可使喉返神经轻瘫/麻痹患者的发声有显著改善,甚至声音完全恢复。采用上述技术之一对声带进行再支配应成为甲状腺和甲状旁腺手术的标准操作,以提高患者的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c34/4746230/8cea236085d9/268_2015_3305_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验