Miyamoto S, Tamiya T, Takatsuka K, Kumamoto Y
Drugs Exp Clin Res. 1985;11(6):383-5.
To assess the rapid bactericidal properties of MT-141, a new cephamycin antibiotic, bacteriological response to MT-141 and latamoxef was compared in complicated urinary tract infections. Although MT-141 was less potent in terms of its MICs than latamoxef against bacterial isolates and was eliminated more slowly than latamoxef from the kidney, MT-141 gave a greater rate of decrease in urinary bacterial counts than latamoxef 6 hours after administration.
为评估新型头孢霉素抗生素MT-141的快速杀菌特性，在复杂性尿路感染中比较了MT-141和拉氧头孢的细菌学反应。尽管MT-141对细菌分离株的最低抑菌浓度（MIC）比拉氧头孢低，且从肾脏清除比拉氧头孢慢，但给药6小时后，MT-141使尿细菌计数下降的速率比拉氧头孢更大。
