Aga Y, Yano M, Ogura K
Hinyokika Kiyo. 1983 Apr;29(4):459-63.
The clinical effectiveness of Cefmetazole, a new cephamycin antibiotic, was studied in 13 cases of complicated urinary tract infection and in 3 cases of acute simple pyelonephritis. The drug was administrated, in 2 or 4 g doses twice a day, by intravenous drip infusion, for 5 to 10 days. The overall clinical effectiveness rate, based on the UTI efficacy evaluation, was 92% for complicated urinary tract infection and 100% for acute simple pyelonephritis. Among 18 strains isolated, 14 strains were eradicated and 4 strains were replaced. The bacteriological efficacy was 100%. No adverse reaction was noted. Cefmetazole was suggested to be a useful antibiotic for the treatment of urinary tract infections.
对新型头孢霉素类抗生素头孢美唑治疗13例复杂性尿路感染和3例急性单纯性肾盂肾炎的临床疗效进行了研究。采用静脉滴注给药,剂量为每日2次,每次2或4g,疗程5至10天。根据尿路感染疗效评估,复杂性尿路感染的总体临床有效率为92%,急性单纯性肾盂肾炎为100%。在分离出的18株菌株中,14株被根除,4株被替代。细菌学疗效为100%。未观察到不良反应。头孢美唑被认为是治疗尿路感染的一种有效抗生素。