Chao D, Hsu Y P, Chan C H, Chen Y A
Int J Zoonoses. 1985 Dec;12(4):323-30.
In a series of immunological studies on Trypanosoma cruzi, the lytic titers of epimastigotes and metacyclic trypomastigotes by sera obtained from normal and infected rodents were compared. Lysis of culture forms of T. cruzi by normal mouse or rat serum was restricted to the epimastigote form. Freezing reduced the lytic titers of rodent sera. This serum lytic activity was also depressed during the acute infection phase. Metacyclic trypomastigotes were more resistant than epimastigotes to both nonspecific and specific lysis by sera, However, provided with fresh complement, antisera collected from mice or rats lysed 12-26% of metacyclic trypomastigotes.
在一系列关于克氏锥虫的免疫学研究中，比较了从正常和感染啮齿动物获得的血清对前鞭毛体和循环后期锥鞭毛体的裂解效价。正常小鼠或大鼠血清对克氏锥虫培养形式的裂解仅限于前鞭毛体形式。冷冻降低了啮齿动物血清的裂解效价。在急性感染期，这种血清裂解活性也会降低。循环后期锥鞭毛体比前鞭毛体对血清的非特异性和特异性裂解更具抗性，然而，加入新鲜补体后，从小鼠或大鼠收集的抗血清可裂解12% - 26%的循环后期锥鞭毛体。
