Gadimova Aysel, Arga Gül, Taşkın Esra Çakmak, Konca Hatice Kübra, Özdemir Halil, Çakmaklı Hasan Fatih, İnce Elif, İleri Talia, Dinçaslan Handan, Taçyıldız Nurdan, Ünal Emel, Ertem Mehmet, İnce Erdal, Çiftçi Ergin
Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Division of Pediatric Infectious Disease, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
J Paediatr Child Health. 2024 Dec;60(12):825-830. doi: 10.1111/jpc.16682. Epub 2024 Oct 11.
Herpes zoster is rarely seen in children, but is more common and more severe in those with underlying medical conditions. The purpose of this study was to comprehensively evaluate cases of herpes zoster in all paediatric patients and to detail the clinical course and complications of this disease in children with and without underlying health problems in terms of similarities and differences.
The course of paediatric patients diagnosed with herpes zoster in a tertiary university hospital over a 19-year period was evaluated from the time of diagnosis, divided into groups with and without underlying disease.
In our study, where we evaluated 150 herpes zoster attacks in 143 children, 79.3% of the patients (n = 119) had underlying diseases, while 20.7% (n = 31) were healthy children. The age at the time of primary varicella-zoster virus and herpes zoster was significantly younger in the group without an underlying disease compared to the group with an underlying disease. Pain was reported more in the healthy group, and the duration of symptoms was longer. Ophthalmic nerve involvement was significantly higher in the group without a known disease. Treatment was administered in 90% of all attacks. In the group with underlying diseases, the duration of intravenous treatment and hospital stay were significantly higher as expected.
This study shows that herpes zoster attacks in healthy children can also progress with severe symptoms and complications. Approaches to reduce the burden of herpes zoster should be adopted and developed for all paediatric patients.
带状疱疹在儿童中较为罕见，但在有基础疾病的儿童中更为常见且病情更严重。本研究的目的是全面评估所有儿科患者的带状疱疹病例，并详细阐述该疾病在有或无基础健康问题的儿童中的临床病程及并发症的异同。
对一所三级大学医院19年间诊断为带状疱疹的儿科患者病程进行评估，从诊断时起，分为有基础疾病组和无基础疾病组。
在我们的研究中，评估了143名儿童的150次带状疱疹发作，79.3%的患者（n = 119）有基础疾病，而20.7%（n = 31）为健康儿童。与有基础疾病组相比，无基础疾病组初次感染水痘 - 带状疱疹病毒及患带状疱疹时的年龄显著更小。健康组报告的疼痛更多，症状持续时间更长。无已知疾病组的眼神经受累显著更高。所有发作中有90%接受了治疗。在有基础疾病组中，静脉治疗时间和住院时间如预期显著更长。
本研究表明，健康儿童的带状疱疹发作也可能出现严重症状和并发症。应为所有儿科患者采用并制定减轻带状疱疹负担的方法。
