Jia Shiyu, Ma Huangshui, Gao Shaojingya, Yang Lei, Sun Qiang
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
Sichuan Provincial Engineering Research Center of Oral Biomaterials, Sichuan University, Chengdu, Sichuan, 610041, China.
Small. 2024 Dec;20(51):e2405019. doi: 10.1002/smll.202405019. Epub 2024 Oct 11.
Thermoelectrics (TEs), enabling the direct conversion between heat and electrical energy, have demonstrated extensive application potential in biomedical fields. Herein, the mechanism of the TE effect, recent developments in TE materials, and the biocompatibility assessment of TE materials are provided. In addition to the fundamentals of TEs, a timely and comprehensive review of the recent progress of advanced TE materials and their applications is presented, including wearable power generation, personal thermal management, and biosensing. In addition, the new-emerged medical applications of TE materials in wound healing, disease treatment, antimicrobial therapy, and anti-cancer therapy are thoroughly reviewed. Finally, the main challenges and future possibilities are outlined for TEs in biomedical fields, as well as their material selection criteria for specific application scenarios. Together, these advancements can provide innovative insights into the development of TEs for broader applications in biomedical fields.
热电材料(TEs)能够实现热能与电能之间的直接转换,已在生物医学领域展现出广泛的应用潜力。本文介绍了热电效应的机制、热电材料的最新进展以及热电材料的生物相容性评估。除了热电材料的基本原理外,还对先进热电材料及其应用的最新进展进行了及时而全面的综述,包括可穿戴发电、个人热管理和生物传感。此外,还对热电材料在伤口愈合、疾病治疗、抗菌治疗和抗癌治疗等新兴医学应用进行了全面综述。最后,概述了热电材料在生物医学领域面临的主要挑战和未来可能性,以及其在特定应用场景下的材料选择标准。这些进展共同为热电材料在生物医学领域更广泛应用的发展提供了创新性见解。