20 国集团 1990 年至 2019 年期间与瓣膜性心脏病相关的心衰负担和时间趋势，以及对 2030 年的预测：2019 年全球疾病负担研究分析。
Burden and Temporal Trends of Valvular Heart Disease-Related Heart Failure From 1990 to 2019 and Projection Up to 2030 in Group of 20 Countries: An Analysis for the Global Burden of Disease Study 2019.
机构信息
Department of Cardiology The Second Affiliated Hospital, School of Medicine, South China University of Technology Guangzhou China.
Department of Cardiology Guangzhou First People's Hospital, South China University of Technology Guangzhou China.
出版信息
J Am Heart Assoc. 2024 Oct 15;13(20):e036462. doi: 10.1161/JAHA.124.036462. Epub 2024 Oct 11.
BACKGROUND
The aim of this study was to characterize the burden of valvular heart disease (VHD)-related heart failure (HF) in Group of 20 (G20) countries.
METHODS AND RESULTS
Using data from the 2019 Global Burden of Disease Study, we estimated VHD-related HF burdens (cases, age-standardized prevalence rates, and years lived with disabilities rates) in G20 countries from 1990 to 2019 by age, sex, and sociodemographic index. The burden of VHD-related HF increased in G20 countries from 1990 to 2019, exhibiting heterogeneity across VHD subtypes. In 2019, Italy, the United States, and the Russian Federation had the highest age-standardized prevalence rates of nonrheumatic VHD-related HF, whereas India, Brazil, and Mexico had the lowest. Rheumatic VHD-related HF was most prevalent in China, India, and Italy, whereas the Republic of Korea, Brazil, and Turkey had the lowest. Nonrheumatic VHD-related HF prevalence peaked among G20 countries in individuals ≥85 years of age, whereas rheumatic VHD-related HF peaked in those 75 to 84 years of age in several countries, including China, India, the Russian Federation, Mexico, Argentina, and Turkey. Age-standardized prevalence rates of nonrheumatic VHD-related HF showed a decreasing trend, more pronounced in women, whereas rheumatic VHD-related HF increased in both sexes, with a lower increase in men. Nonrheumatic VHD-related HF burden correlated with age and sociodemographic index, whereas rheumatic VHD-related HF burden was highest in middle sociodemographic index countries for those <75 years of age. Years lived with disabilities rates for VHD-related HF represented about 9.0% of the overall burden across populations.
CONCLUSIONS
The increasing burden of VHD-related HF in G20 countries highlights the need for timely interventions to mitigate this growing public health challenge.
背景
本研究旨在描述 20 国集团（G20）国家中与瓣膜性心脏病（VHD）相关的心衰（HF）负担。
方法和结果
我们使用 2019 年全球疾病负担研究的数据，根据年龄、性别和社会人口指数，估计了 G20 国家 1990 年至 2019 年 VHD 相关 HF 的负担（病例数、年龄标准化患病率和残疾生活年率）。1990 年至 2019 年，G20 国家 VHD 相关 HF 的负担增加，不同 VHD 亚型存在差异。2019 年，意大利、美国和俄罗斯联邦的非风湿性 VHD 相关 HF 年龄标准化患病率最高，而印度、巴西和墨西哥最低。风湿性 VHD 相关 HF 在中国、印度和意大利最为普遍，而韩国、巴西和土耳其则最低。非风湿性 VHD 相关 HF 患病率在 G20 国家中在≥85 岁人群中达到峰值，而在包括中国、印度、俄罗斯联邦、墨西哥、阿根廷和土耳其在内的几个国家中，风湿性 VHD 相关 HF 则在 75 至 84 岁人群中达到峰值。非风湿性 VHD 相关 HF 的年龄标准化患病率呈下降趋势，在女性中更为明显，而风湿性 VHD 相关 HF 在两性中均呈上升趋势，男性上升幅度较小。非风湿性 VHD 相关 HF 的负担与年龄和社会人口指数相关，而在<75 岁的人群中，风湿性 VHD 相关 HF 的负担在中等社会人口指数国家最高。VHD 相关 HF 的残疾生活年率占人群总体负担的 9.0%左右。
结论
G20 国家中 VHD 相关 HF 负担的增加突出表明，需要及时采取干预措施来减轻这一日益严重的公共卫生挑战。
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