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骨质疏松性椎体压缩性骨折的椎体增强:目前的证据支持和反对的是什么?

Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures: What is the Current Evidence Pro and Con?

机构信息

Department of Radiology, Albert Einstein College of Medicine, Jacobi Medical Center, 1400 Pelham Pkwy South, Bronx, NY 10461, USA.

Department of Radiology, Albert Einstein College of Medicine, Jacobi Medical Center, 1400 Pelham Pkwy South, Bronx, NY 10461, USA.

出版信息

Radiol Clin North Am. 2024 Nov;62(6):979-991. doi: 10.1016/j.rcl.2024.03.004. Epub 2024 Apr 23.

DOI:10.1016/j.rcl.2024.03.004
PMID:39393856
Abstract

Osteoporotic vertebral compression fractures can be quite challenging to treat, especially since they often occur in older adults and can be associated with significant morbidity and mortality. The standard treatment for these fractures has been medical management, as many of these patients are not candidates for open surgery. Vertebral augmentation procedures have emerged as another treatment option. Though initially accepted by clinicians, the benefit of these procedures has been questioned by several clinical trials. Safety concerns related to adjacent level fractures and cement extravasation have also been raised. We review these controversies in the context of the current literature.

摘要

骨质疏松性椎体压缩骨折的治疗颇具挑战性,尤其是这些骨折常发生于老年人,且常与较高的发病率和死亡率相关。这些骨折的标准治疗方法是药物治疗,因为许多患者不适合接受开放性手术。椎体增强术已成为另一种治疗选择。尽管最初被临床医生所接受,但这些手术的益处已被多项临床试验所质疑。与相邻节段骨折和水泥渗漏相关的安全性问题也已被提出。我们在当前文献的背景下对这些争议进行了回顾。

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