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预浸骨水泥明胶海绵条在老年骨质疏松性胸腰椎压缩骨折经皮椎体后凸成形术中封闭椎体前壁缺损的作用:一项回顾性研究

The Role of Pre-soaked Bone Cement Gelatin Sponge Strips in Sealing Anterior Vertebral Wall Defects During Percutaneous Kyphoplasty for Osteoporotic Thoracolumbar Compression Fractures in the Elderly: A Retrospective Study.

作者信息

Sun Chong, Cao Shuwen, Gao Yang, Wang Quanfa, Wang Mingzheng, Zheng Zhaojun, Wang Jirong, Zheng Kai

机构信息

Department of Spinal Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.

College of Mechanical and Electrical Engineering, Qingdao University, Qingdao, China.

出版信息

Global Spine J. 2025 Sep 9:21925682251379024. doi: 10.1177/21925682251379024.

DOI:10.1177/21925682251379024
PMID:40925356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12420642/
Abstract

Study DesignRetrospective cohort study.ObjectivesUnilateral percutaneous kyphoplasty (PKP) is widely used to treat osteoporotic vertebral compression fractures (OVCF) in elderly patients. Cement leakage is the most common complication and may cause serious consequences. Although various techniques have been proposed to reduce leakage, few studies have addressed cases with preexisting anterior vertebral wall defects. This study aims to evaluate whether intraoperative sealing of these defects with gelatin sponge strips pre-soaked in bone cement can reduce leakage and improve surgical outcomes.MethodsA retrospective analysis was conducted on 86 patients who underwent unilateral single-level PKP for thoracolumbar OVCF from December 2021 to October 2024. All patients had preoperative cortical defects in the anterior vertebral wall and were divided into two groups: Group A (n = 43) received conventional PKP, while Group B (n = 43) underwent PKP with defect sealing using pre-soaked gelatin sponge strips. Clinical and radiological assessments were performed preoperatively, immediately postoperatively, at 3 months, and at 12 months.ResultsBoth groups achieved favorable outcomes without severe complications. Cement leakage at the anterior vertebral wall was significantly lower in Group B than in Group A ( = 0.007). Group B also demonstrated better cement diffusion ( = 0.013) and a higher cement injection volume ( = 0.022).ConclusionsIn elderly patients with thoracolumbar OVCF and anterior vertebral cortical defects, unilateral puncture PKP combined with bone cement-soaked gelatin sponge strips effectively reduces anterior vertebral wall cement leakage and improves cement distribution, which may contribute to better procedural safety and stability.

摘要

研究设计

回顾性队列研究。

目的

单侧经皮椎体后凸成形术(PKP)广泛用于治疗老年骨质疏松性椎体压缩骨折(OVCF)。骨水泥渗漏是最常见的并发症,可能导致严重后果。尽管已提出多种技术来减少渗漏,但很少有研究涉及存在椎体前壁缺损的病例。本研究旨在评估术中用预浸骨水泥的明胶海绵条封闭这些缺损是否能减少渗漏并改善手术效果。

方法

对2021年12月至2024年10月期间接受单侧单节段PKP治疗胸腰椎OVCF的86例患者进行回顾性分析。所有患者术前椎体前壁均有皮质缺损,分为两组:A组(n = 43)接受传统PKP,B组(n = 43)采用预浸明胶海绵条封闭缺损的PKP。在术前、术后即刻、3个月和12个月进行临床和影像学评估。

结果

两组均取得良好效果,无严重并发症。B组椎体前壁骨水泥渗漏明显低于A组(P = 0.007)。B组骨水泥弥散也更好(P = 0.013),骨水泥注入量更高(P = 0.022)。

结论

对于胸腰椎OVCF且椎体前皮质缺损的老年患者,单侧穿刺PKP联合骨水泥浸泡的明胶海绵条可有效减少椎体前壁骨水泥渗漏,改善骨水泥分布,这可能有助于提高手术安全性和稳定性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239c/12420642/9c2c98530ceb/10.1177_21925682251379024-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239c/12420642/a8b5a15970be/10.1177_21925682251379024-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239c/12420642/fef91ba0a549/10.1177_21925682251379024-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239c/12420642/9c2c98530ceb/10.1177_21925682251379024-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239c/12420642/a8b5a15970be/10.1177_21925682251379024-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239c/12420642/fef91ba0a549/10.1177_21925682251379024-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239c/12420642/9c2c98530ceb/10.1177_21925682251379024-fig3.jpg

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