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血液系统恶性肿瘤中性粒细胞减少患者持续性发热的非感染性病因异质性综合征:管理的另一个契机?

The Heterogeneous Syndrome of Noninfectious Causes of Persistent Fever in Neutropenic Patients With Hematologic Malignancy: Another Opportunity for Stewardship?

作者信息

Aslan Abdullah Tarik, Akova Murat, Kontoyiannis Dimitrios P

机构信息

UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, Australia.

Department of Infectious Diseases and Clinical Microbiology, School of Medicine, Hacettepe University, Ankara, Turkey.

出版信息

Clin Infect Dis. 2024 Dec 17;79(6):1333-1337. doi: 10.1093/cid/ciae487.

Abstract

Although occult fungal, viral, and multidrug-resistant bacterial infections can cause persistent fever in neutropenic patients with hematologic cancer, a variety of noninfectious entities should be considered on a case-by-case basis in the context of negative diagnostic workup for infection.

摘要

尽管隐匿性真菌、病毒和耐多药细菌感染可导致血液系统癌症中性粒细胞减少患者持续发热,但在感染诊断检查结果为阴性的情况下,应根据具体病例考虑多种非感染性病因。

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