Nikolić Nikola, Sculthorpe Catherine, Stock Jessica, Stevens Dan, Eccles Jessica
Early Intervention in Psychosis Service, Sussex Partnership NHS Foundation Trust, Worthing, UK.
Advanced Clinical Practice and Non-Medical Prescribing Department, London South Bank University, UK.
BJPsych Bull. 2024 Oct 14:1-6. doi: 10.1192/bjb.2024.64.
We explored the prevalence of autism and attention-deficit hyperactivity disorder in first-episode psychosis. Through service evaluation involving 509 individuals, detailed analyses were conducted on neurodevelopmental traits and patterns of service utilisation.
Prevalence of neurodivergence in first-episode psychosis was 37.7%. Neurodivergent individuals used urgent mental health services more frequently (Mann-Whitney = 25925, = -2.832, = 0.005) and had longer hospital stays (Mann-Whitney = 22816, = -4.886, ≤ 0.001) than non-neurodivergent people. Neurodivergent people spend more than twice as long in mental health hospitals at a time than the non-neurodivergent people (Mann-Whitney = 22 909.5, = -4.826, ≤ 0.001). Mediation analysis underscored indirect impact of neurodivergence on hospital stay durations through age at onset of psychosis and use of emergency services.
Prevalence of neurodevelopmental conditions in first-episode psychosis is underestimated. Neurodivergent individuals show increased utilisation of mental health services and experience psychosis earlier. Early assessment is crucial for optimising psychosis management and improving mental health outcomes.
我们探讨了首发精神病患者中自闭症和注意力缺陷多动障碍的患病率。通过对509名个体的服务评估，对神经发育特征和服务利用模式进行了详细分析。
首发精神病患者中神经发育异常的患病率为37.7%。与神经发育正常的人相比，神经发育异常的个体更频繁地使用紧急心理健康服务（曼-惠特尼U = 25925，z = -2.832，p = 0.005），住院时间更长（曼-惠特尼U = 22816，z = -4.886，p≤0.001）。神经发育异常的人在精神科医院的单次住院时间是非神经发育异常者的两倍多（曼-惠特尼U = 22909.5，z = -4.826，p≤0.001）。中介分析强调了神经发育异常通过精神病发作年龄和急诊服务使用情况对住院时间的间接影响。
首发精神病患者中神经发育疾病的患病率被低估。神经发育异常的个体心理健康服务利用率更高，精神病发作更早。早期评估对于优化精神病管理和改善心理健康结果至关重要。
