Pharmacy Directorate, University of Ghana Medical Centre, Legon, Accra, Ghana.
Department of Surgery, University of Ghana Medical School, College of Health Sciences, University of Ghana, Korle Bu, Accra, Ghana.
Ghana Med J. 2024 Sep;58(3):207-214. doi: 10.4314/gmj.v58i3.5.
The study aimed to assess antibiotic prescribing and use patterns at the Department of Surgery, Korle Bu Teaching Hospital.
A cross-sectional study design was employed in this study.
The study was conducted at the Department of Surgery, Korle Bu Teaching Hospital.
Forty-two prescribers out of 63 (67%) at the Department of Surgery responded to questionnaires. Over the study period, prescriptions and medical records of 1715 patients from the general surgery, neurosurgery, and urology units were reviewed.
Percentage of prescriptions with antibiotics, percentage of prescribers using guidelines for antibiotic prescriptions, and percentage using culture and sensitivity to inform antibiotic prescriptions.
Of the 1715 prescriptions assessed, 75% (1294/1715) were from inpatients, and 45% (772/1715) included an antibiotic. Ciprofloxacin and metronidazole constituted 54% of antibiotic prescriptions from general surgery. Amoxicillin/clavulanic acid and ceftriaxone constituted 64.7% of antibiotic prescriptions from neurosurgery, and ceftriaxone and ciprofloxacin made up 37.7% of antibiotic prescriptions from urology. Microbiology testing was done for only 14.5% (9/62) of inpatients who received antibiotics for treatment. The choice of antibiotics was influenced mainly by doctors' previous experience (37/42, 88.1%).
Antibiotics are widely used. About half of all prescriptions had antibiotics, with ciprofloxacin and metronidazole constituting more than half of antibiotic prescriptions from general surgery. Doctors mainly based their antibiotic prescriptions on previous experience and occasionally on microbiological investigations.
None declared.
本研究旨在评估科勒布教学医院外科的抗生素处方和使用模式。
本研究采用横断面研究设计。
本研究在科勒布教学医院外科进行。
外科 63 名开方医生中有 42 名（67%）对问卷做出回应。在研究期间，回顾了普通外科、神经外科和泌尿科的 1715 名患者的处方和病历。
带抗生素的处方比例、使用抗生素处方指南的开方医生比例、以及使用培养和药敏试验来指导抗生素处方的比例。
在所评估的 1715 张处方中，75%（1294/1715）来自住院患者，其中 45%（772/1715）包含抗生素。普通外科的抗生素处方中，环丙沙星和甲硝唑占 54%。神经外科的抗生素处方中，阿莫西林/克拉维酸和头孢曲松占 64.7%，泌尿科的抗生素处方中，头孢曲松和环丙沙星占 37.7%。只有 14.5%（9/62）接受抗生素治疗的住院患者进行了微生物学检测。抗生素的选择主要受医生以往经验的影响（37/42，88.1%）。
抗生素的使用非常广泛。约一半的处方都包含抗生素，其中环丙沙星和甲硝唑占普通外科抗生素处方的一半以上。医生主要根据以往的经验，偶尔根据微生物学检查来开具抗生素处方。
无。
