Department of Pharmacy, Ghana Police Hospital, Accra, Ghana.
Scottish Antimicrobial Prescribing Group, Healthcare Improvement Scotland, Glasgow, United Kingdom.
Pan Afr Med J. 2021 Aug 2;39:222. doi: 10.11604/pamj.2021.39.222.29569. eCollection 2021.
irrational or inappropriate prescribing of antibiotics is a major problem in healthcare and leads to antibiotic resistance. There is the need to understand the prescribing patterns and antibiotic stewardship in health facilities to support appropriate antibiotic use. A study was carried out to evaluate prescribing pattern of antibiotics at the Ghana Police Hospital using National Standard Treatment Guidelines (STG) and World Health Organization (WHO) prescribing indicators.
a cross-sectional descriptive study was conducted at the Ghana Police Hospital. Data on prescriptions of antibiotics for both out-patients and in-patients was collected between December 2019 and March 2020. A pretested self-designed tool was used for data collection. All sampled prescriptions were assessed for appropriateness using the STG of 2017 and WHO "AWaRe" classification. The criteria used in assessment included dose, frequency, duration of treatment and choice of antibiotic prescribed for disease condition. Descriptive statistics were used in data analysis.
a total of 184 patient prescriptions (286 antibiotics) were included in this study. Results showed that antibiotics were mostly prescribed for dental and dental-related conditions (20.7%) and obstetric post-delivery prophylaxis (18.1%). Appropriateness of indicators for antibiotics prescribed assessed ranged between 89.2% to 97.6%. The most frequently prescribed antibiotics were metronidazole (25.9%), amoxicillin with clavulanic acid (22.0%), amoxicillin (16.4%) and ciprofloxacin (10.1%). Based on WHO "AWaRe" classification, the "access" group of antibiotics (74%) was the most prescribed, followed by "watch" group (24%). There were no antibiotics prescribed from the "reserve" group of antibiotics and another 2% that was not part of AwaRe classification.
study revealed that the level of appropriateness for prescribing indicators assessed was relatively high and majority of prescribed antibiotics were from the "access" and "watch" group. These observations suggest responsible prescribing of antibiotics at the Ghana Police Hospital and effective antibiotic stewardship should be sustained and improved.
不合理或不适当的抗生素处方是医疗保健中的一个主要问题，会导致抗生素耐药性。有必要了解卫生机构的处方模式和抗生素管理情况，以支持合理使用抗生素。本研究旨在使用国家治疗标准指南（STG）和世界卫生组织（WHO）处方指标评估加纳警察医院的抗生素处方模式。
在加纳警察医院进行了一项横断面描述性研究。2019 年 12 月至 2020 年 3 月期间收集了门诊和住院患者的抗生素处方数据。使用预先测试的自我设计工具进行数据收集。使用 2017 年 STG 和世卫组织“AWaRe”分类评估所有抽样处方的适宜性。评估标准包括剂量、频率、治疗持续时间和所开抗生素对疾病状况的选择。数据分析采用描述性统计。
本研究共纳入 184 例患者处方（286 种抗生素）。结果表明，抗生素主要用于牙科和牙科相关疾病（20.7%）和产科产后预防（18.1%）。评估的抗生素处方指标适宜性在 89.2%至 97.6%之间。最常开的抗生素是甲硝唑（25.9%）、阿莫西林克拉维酸（22.0%）、阿莫西林（16.4%）和环丙沙星（10.1%）。根据世卫组织“AWaRe”分类，“准入”类抗生素（74%）的处方最多，其次是“监控”类（24%）。没有处方“储备”类抗生素，另有 2%不属于“AWaRe”分类。
研究表明，评估的处方指标适宜性水平相对较高，大多数开的抗生素来自“准入”和“监控”类。这些观察结果表明，加纳警察医院的抗生素处方负责任，有效的抗生素管理应得到维持和改善。
