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一名新冠病毒感染康复患者的股骨远端骨关节毛霉菌病

Osteoarticular mucormycosis of the distal femur in a post COVID-19 patient.

作者信息

Kasha Srinivas, Palakurthi Venugopal, Yalamanchili Ranjith Kumar, Yashavant Patil Pratik, Gprk Rohith

机构信息

Orthopaedics, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India.

Orthopaedics, GMC, Jangaon, Telangana, India.

出版信息

Med Mycol Case Rep. 2024 Sep 16;46:100670. doi: 10.1016/j.mmcr.2024.100670. eCollection 2024 Dec.

Abstract

A 38 year old man with no known comorbidities presented with pain and swelling over the knee joint a few days after recovery from severe COVID-19. Initial debridement and cultures revealed growth of Mucorales affecting a large segment of the distal femur with also positive cultures obtained from the maxillary sinus and the lower lobe of the right lung. Due to this involvement of a long segment of the femur, right lung and left maxillary sinus, a multidisciplinary approach of above knee amputation along with debridement of left maxillary sinus and lobectomy of right lung lower lobe was performed to decrease the fungal load and favour good prognosis. This report warrants the need for early imaging and surgical debridement of tissue for fungal cultures and biopsy in immunocompromised individuals.

摘要

一名38岁无已知合并症的男性在重症COVID-19康复几天后出现膝关节疼痛和肿胀。初始清创和培养显示毛霉目生长,累及股骨远端大部分区域,上颌窦和右肺下叶培养也呈阳性。由于股骨长段、右肺和左上颌窦受累,采取了多学科方法,进行了膝上截肢术,同时对上颌窦进行清创及右肺下叶肺叶切除术,以减少真菌负荷并利于良好预后。本报告表明免疫功能低下个体需要早期进行影像学检查以及对组织进行手术清创以进行真菌培养和活检。

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