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济州黑猪和三元杂交猪肽提取物生物利用度的比较研究。

Comparative study on the bioavailability of peptide extracts from Jeju black pigs and three-way crossbred pigs.

作者信息

Jeong Jae Won, Mariano Ermie, Lee Da Young, Lee Seung Yun, Kim Jae Hyeon, Yun Seung Hyeon, Lee Juhyun, Park Jinmo, Choi Yeongwoo, Han Dahee, Kim Jin Soo, Hur Sun Jin

机构信息

Department of Animal Science and Technology, Chung-Ang University, Anseong 17546, Korea.

Division of Animal Science, Institute of Agriculture & Life Science, Gyeongsang National University, Jinju 52828, Korea.

出版信息

J Anim Sci Technol. 2024 Sep;66(5):1049-1068. doi: 10.5187/jast.2023.e86. Epub 2024 Sep 30.

Abstract

This study aimed to compare the changes in the bioactivities of peptide extracts (< 10 kDa) obtained from Jeju black pigs (JBP) and three-way crossbred pigs (Landrace × Yorkshire × Duroc, LYD) before and after digestion. The results showed that the loin peptide extracts of JBP maintained high 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity after digestion. However, the iron chelating activity and antihypertensive activity of all peptide extracts were decreased. This study suggested that the peptide extracts produced through alkaline-AK digestion have sufficiently high antioxidant and antihypertensive activities; however, these activities were reduced after digestion. Meanwhile, the JBP loin and ham peptide extracts promoted high superoxide dismutase (SOD) activity than that of LYD when administered to mice. Furthermore, the ham peptide extracts of JBP showed a relatively high antihypertensive activity in mice. Therefore, it is deemed that these peptide extracts from JBP are more bioactive than that of LYD, and can be used as bioactive materials.

摘要

本研究旨在比较济州黑猪(JBP)和三元杂交猪(长白猪×约克夏猪×杜洛克猪,LYD)来源的肽提取物(<10 kDa)在消化前后生物活性的变化。结果表明,JBP的腰部肽提取物在消化后仍保持较高的2,2'-联氮-双-(3-乙基苯并噻唑啉-6-磺酸)(ABTS)自由基清除活性。然而,所有肽提取物的铁螯合活性和降压活性均降低。本研究表明,通过碱性AK消化产生的肽提取物具有足够高的抗氧化和降压活性;然而,这些活性在消化后降低。同时,当给小鼠施用时,JBP的腰部和火腿肽提取物比LYD的提取物促进更高的超氧化物歧化酶(SOD)活性。此外,JBP的火腿肽提取物在小鼠中显示出相对较高的降压活性。因此,认为这些来自JBP的肽提取物比LYD的提取物具有更高的生物活性,可作为生物活性材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d01/11466743/8719d042031d/jast-66-5-1049-g1.jpg

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