伴有正常左心房的混合性Cpc-肺动脉高压和射血分数保留的心力衰竭的心室相互依赖表型：对心肺运动试验指标和临床结局的影响
Ventricular interdependent phenotype of mixed Cpc-pulmonary hypertension and HFpEF with normal left atrium: Impact on CPET metrics and clinical outcomes.
作者信息
Zampierollo-Jaramillo Giovanna, Abed Anas, El Shaer Ahmed, Garcia-Arango Mariana, Chen Yimin, Tehrani Babak, Tu Wanxin, Arif Abdul Wahab, Heffernan Shannon, Esmaeeli Amir, Sahai Aditya, Runo James, Baber Aurangzeb, Masri Sofia C, Raza Farhan
机构信息
Department of Internal Medicine University of Wisconsin-Madison Madison Wisconsin USA.
Department of Medicine-Cardiovascular Division University of Wisconsin-Madison Madison Wisconsin USA.
出版信息
Pulm Circ. 2024 Oct 11;14(4):e12449. doi: 10.1002/pul2.12449. eCollection 2024 Oct.
Among 45 CpcPH/heart failure with preserved ejection fraction participants, 11 with normal left atrium (compared to 34 with abnormal left atrium, < 0.05 for all) had low left ventricle (LV) transmural pressure (2.9 ± 2.4 vs. 6.2 ± 2.9 mmHg), and increased right ventricle (RV):LV ratio (2.41 ± 1.09 vs. 1.46 ± 0.66) and interventricular septal angle (149 ± 8 vs. 136 ± 10), indicating exaggerated ventricular interdependence from a dilated RV.
在45例射血分数保留的CpcPH/心力衰竭参与者中，11例左心房正常（与34例左心房异常相比，所有指标P<0.05）的左心室跨壁压较低（2.9±2.4对6.2±2.9mmHg），右心室（RV）与左心室（LV）的比值增加（2.41±1.09对1.46±0.66）以及室间隔角增大（149±8对136±10），表明右心室扩张导致心室相互依赖加剧。
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