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一种利用高阶像差上皮补偿治疗和地形图引导消融治疗放射状角膜切开术(RK)引起的角膜不规则性的新方法——CREATE方案。

A Novel Procedure for Treating Radial Keratotomy (RK) Induced Corneal Irregularity Utilizing Treatment of Epithelial Compensation of Higher-Order Aberrations and Topographic Guided Ablation-The CREATE Protocol.

作者信息

Motwani Manoj

机构信息

Cornea Revolution/Motwani LASIK Institute, San Diego, CA, 92121, USA.

出版信息

Clin Ophthalmol. 2024 Oct 7;18:2813-2820. doi: 10.2147/OPTH.S476555. eCollection 2024.

Abstract

PURPOSE

To present the outcomes of a retrospective study of treatment of radial keratotomy-induced corneal irregularity with topographic guided ablation and a trans-epithelial approach based on epithelial compensation.

METHODS

Sixty eyes of 31 patients were treated for radial keratotomy-induced corneal irregularity utilizing a customized trans-epithelial topographic guided ablation photorefractive keratectomy (PRK) for treatment of corneal higher-order aberrations and lower-order astigmatism. Three-month results were analyzed via measurement of vision, refraction, residual higher-order aberrations (HOAs), residual lower-order and higher-order aberrations, as well as for loss or gains of lines of best corrected visual acuity.

RESULTS

Higher-order aberrations (HOA) were reduced by 69%, with an 80% reduction of higher-order aberrations grouped with lower-order aberrations (Grouped). Most (95%) of eyes achieved 20/40 vision or better, 50% of eyes gained 1-9 lines of best corrected vision, and no eyes had loss of best corrected vision.

CONCLUSION

Use of the CREATE protocol to treat RK-induced corneal irregularity resulted in a significant decrease in HOA, as well as a significant improvement in corrected distance visual acuity.

摘要

目的

介绍一项回顾性研究的结果,该研究采用基于上皮补偿的地形引导消融和经上皮方法治疗放射状角膜切开术引起的角膜不规则性。

方法

对31例患者的60只眼睛进行治疗,利用定制的经上皮地形引导消融准分子激光原位角膜磨镶术(PRK)治疗角膜高阶像差和低阶散光引起的放射状角膜切开术诱导的角膜不规则性。通过测量视力、验光、残余高阶像差(HOA)、残余低阶和高阶像差,以及最佳矫正视力行数的增减来分析三个月的结果。

结果

高阶像差(HOA)降低了69%,高阶像差与低阶像差合并(分组)降低了80%。大多数(95%)的眼睛达到了20/40或更好的视力,50%的眼睛最佳矫正视力提高了1-9行,没有眼睛的最佳矫正视力下降。

结论

使用CREATE方案治疗RK诱导的角膜不规则性导致HOA显著降低,矫正远视力也有显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6576/11468286/b6a4a27c1966/OPTH-18-2813-g0001.jpg

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