Wu Gangyue, Dai Xiaodan, Tian Junchi, Sun Jingru
Jinhua Eye Hospital Jinhua 321000, Zhejiang, China.
Am J Transl Res. 2024 Sep 15;16(9):4903-4911. doi: 10.62347/DTLF6342. eCollection 2024.
To evaluate the efficacy of repeated low-level red-light (RLRL) therapy combined with optical lenses in children and adolescents with myopia.
This retrospective study included 108 children and adolescents. Based on the difference in the combination intervention scheme participants were divided into four groups based on the intervention they received: the RLRL+orthokeratology (OK) lens intervention group (RLRL+OK group), the RLRL+defocus distributed multi-point (DDM) lens intervention group (RLRL+DDM group), the RLRL+single-vision spectacles (SVS) intervention group (RLRL+SVS group), and a control group. Visual acuity, spherical equivalent refraction (SER), and axial length (AL) were measured before and after the intervention. Binary logistic regression was used to identify factors influencing vision recovery.
The SER and AL at baseline were statistically different (<0.01). After the intervention, the AL increase in the RLRL+OK, RLRL+DDM, and RLRL+SVS groups was significantly better than the control group across time points (<0.001). Changes in SER were also statistically significant in the RLRL+DDM and RLRL+SVS groups compared to the control group across time points (<0.001). The intervention method was identified as a significant factor influencing vision recovery (<0.001).
RLRL therapy combined with optical lenses is effective in controlling myopia progression in children and adolescents.
评估重复低强度红光（RLRL）疗法联合光学镜片对儿童和青少年近视的疗效。
这项回顾性研究纳入了108名儿童和青少年。根据联合干预方案的差异，参与者根据所接受的干预分为四组：RLRL+角膜塑形术（OK）镜片干预组（RLRL+OK组）、RLRL+离焦分散多点（DDM）镜片干预组（RLRL+DDM组）、RLRL+单焦点眼镜（SVS）干预组（RLRL+SVS组）和对照组。在干预前后测量视力、等效球镜度（SER）和眼轴长度（AL）。采用二元逻辑回归分析确定影响视力恢复的因素。
基线时的SER和AL在统计学上存在差异（<0.01）。干预后，RLRL+OK组、RLRL+DDM组和RLRL+SVS组在各时间点的AL增加均显著优于对照组（<0.001）。与对照组相比，RLRL+DDM组和RLRL+SVS组在各时间点的SER变化也具有统计学意义（<0.001）。干预方法被确定为影响视力恢复的重要因素（<0.001）。
RLRL疗法联合光学镜片可有效控制儿童和青少年近视的进展。
