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腹壁生物力学的数值模拟及用于模型验证的实验分析。

Numerical modeling of the abdominal wall biomechanics and experimental analysis for model validation.

作者信息

Spadoni Silvia, Todros Silvia, Pavan Piero G

机构信息

Department of Industrial Engineering, University of Padova, Padova, Italy.

Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy.

出版信息

Front Bioeng Biotechnol. 2024 Sep 27;12:1472509. doi: 10.3389/fbioe.2024.1472509. eCollection 2024.

Abstract

The evaluation of the biomechanics of the abdominal wall is particularly important to understand the onset of pathological conditions related to weakening and injury of the abdominal muscles. A better understanding of the biomechanics of the abdominal wall could be a breakthrough in the development of new therapeutic approaches. For this purpose, several studies in the literature propose finite element models of the human abdomen, based on the geometry of the abdominal wall from medical images and on constitutive formulations describing the mechanical behavior of fascial and muscular tissues. The biomechanics of the abdominal wall depends on the passive mechanical properties of fascial and muscle tissue, on the activation of abdominal muscles, and on the variable intra-abdominal pressure. To assess the quantitative contribution of these features to the development and validation of reliable numerical models, experimental data are fundamental. This work presents a review of the state of the art of numerical models developed to investigate abdominal wall biomechanics. Different experimental techniques, which can provide data for model validation, are also presented. These include electromyography, ultrasound imaging, intraabdominal pressure measurements, abdominal surface deformation, and stiffness/compliance measurements.

摘要

评估腹壁的生物力学对于理解与腹部肌肉弱化和损伤相关的病理状况的发病机制尤为重要。更好地理解腹壁的生物力学可能是开发新治疗方法的一个突破。为此,文献中的几项研究基于医学图像的腹壁几何形状以及描述筋膜和肌肉组织力学行为的本构公式,提出了人体腹部的有限元模型。腹壁的生物力学取决于筋膜和肌肉组织的被动力学特性、腹部肌肉的激活以及变化的腹内压。为了评估这些特征对可靠数值模型的开发和验证的定量贡献,实验数据至关重要。这项工作对为研究腹壁生物力学而开发的数值模型的现状进行了综述。还介绍了可以为模型验证提供数据的不同实验技术。这些技术包括肌电图、超声成像、腹内压测量、腹部表面变形以及刚度/顺应性测量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c06/11466767/6537aa579da2/fbioe-12-1472509-g001.jpg

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