Science Writer, Rockefeller University Press, New York, NY, USA.
J Gen Physiol. 2024 Nov 4;156(11). doi: 10.1085/jgp.202413675. Epub 2024 Oct 14.
Two JGP studies (Sanchez et al. https://doi.org/10.1085/jgp.202313502; Kraujaliene et al. https://doi.org/10.1085/jgp.202413600) reveal how small differences in a pore-lining region alter both the gap junction and hemichannel function of connexin26 and connexin30.
两篇 JGP 研究(Sanchez 等人,https://doi.org/10.1085/jgp.202313502;Kraujaliene 等人,https://doi.org/10.1085/jgp.202413600)揭示了连接蛋白 26 和 30 中孔衬区域的微小差异如何改变缝隙连接和半通道的功能。