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免疫功能正常患者的脊髓硬膜下积脓:病例说明

Spinal subdural empyema in an immunocompetent patient: illustrative case.

作者信息

Thiruvengadam Shreyas, Khoo Boyuan, Saha Snigdha

机构信息

Department of Neurosurgery, Sir Charles Gairdner Hospital, Perth, Western Australia.

出版信息

J Neurosurg Case Lessons. 2024 Oct 14;8(16). doi: 10.3171/CASE24464.

Abstract

BACKGROUND

Spinal subdural empyemas are a rare presentation of rapid neurological decline, progressing from radiculopathy to complete paralysis and sensory loss. Although pathogenic mechanisms have been hypothesized, their occurrence in this population of patients remains unclear.

OBSERVATIONS

The authors present the third documented case of an isolated spinal subdural empyema of unclear etiology in an immunocompetent patient with no established risk factors.

LESSONS

Successful treatment requires prompt clinical suspicion, radiological diagnosis, and surgical evacuation along with empirical antibiotic treatment. Radiological clarification of the subdural versus the epidural location of the empyema is difficult, while intraoperative durotomy for exploration risks subdural dissemination. In these cases, intraoperative ultrasonography would be a useful adjunct and decision aid. https://thejns.org/doi/10.3171/CASE24464.

摘要

背景

脊髓硬膜下积脓是一种罕见的导致神经功能迅速衰退的病症,可从神经根病发展为完全性瘫痪和感觉丧失。尽管已经对其发病机制进行了推测,但在这类患者群体中的发生情况仍不清楚。

观察结果

作者报告了第三例有记录的病因不明的孤立性脊髓硬膜下积脓病例,该患者免疫功能正常,无既定风险因素。

经验教训

成功的治疗需要临床及时怀疑、进行放射学诊断、手术引流以及经验性抗生素治疗。要明确积脓位于硬膜下还是硬膜外很难,而术中切开硬脑膜进行探查有导致硬膜下扩散的风险。在这些病例中,术中超声检查将是一种有用的辅助手段和决策辅助工具。https://thejns.org/doi/10.3171/CASE24464

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