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脊柱硬膜外脓肿

Spinal epidural abscess.

作者信息

Tompkins Marc, Panuncialman Ian, Lucas Phillip, Palumbo Mark

机构信息

Department of Orthopaedic Surgery, Brown Alpert Medical School, Providence, Rhode Island 02903, USA.

出版信息

J Emerg Med. 2010 Sep;39(3):384-90. doi: 10.1016/j.jemermed.2009.11.001. Epub 2010 Jan 8.

Abstract

BACKGROUND

Spinal epidural abscess is an uncommon disease with a relatively high rate of associated morbidity and mortality. The most important determinant of outcome is early diagnosis and initiation of appropriate treatment.

OBJECTIVES

We aim to highlight the clinical manifestations, describe the early diagnostic evaluation, and outline the treatment principles for spinal epidural abscess in the adult.

DISCUSSION

Spinal epidural abscess should be suspected in the patient presenting with complaints of back pain or a neurologic deficit in conjunction with fever or an elevated erythrocyte sedimentation rate. Gadolinium-enhanced magnetic resonance imaging is the diagnostic modality of choice to confirm the presence and determine the location of the abscess. Emergent surgical decompression and debridement (with or without spinal stabilization) followed by long-term antimicrobial therapy remains the treatment of choice. In select cases, non-operative management can be cautiously considered when the risk of neurologic complications is determined to be low.

CONCLUSION

Patients with a spinal epidural abscess often present first in the emergency department setting. It is imperative for the emergency physician to be familiar with the clinical features, diagnostic work-up, and basic management principles of spinal epidural abscess.

摘要

背景

脊柱硬膜外脓肿是一种罕见疾病,其相关的发病率和死亡率相对较高。预后的最重要决定因素是早期诊断和开始适当治疗。

目的

我们旨在强调临床表现,描述早期诊断评估,并概述成人脊柱硬膜外脓肿的治疗原则。

讨论

对于出现背痛或神经功能缺损并伴有发热或红细胞沉降率升高的患者,应怀疑脊柱硬膜外脓肿。钆增强磁共振成像(Gd-MRI)是确认脓肿存在并确定其位置的首选诊断方法。紧急手术减压和清创(有或无脊柱稳定),随后进行长期抗菌治疗仍然是首选治疗方法。在某些情况下,当确定神经并发症风险较低时,可以谨慎考虑非手术治疗。

结论

脊柱硬膜外脓肿患者通常首先在急诊科就诊。急诊医生必须熟悉脊柱硬膜外脓肿的临床特征、诊断检查和基本治疗原则。

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