Mitelman F
Cancer Genet Cytogenet. 1986 Jan 1;19(1-2):67-71. doi: 10.1016/0165-4608(86)90373-0.
It is becoming increasingly difficult to assimilate in a meaningful fashion the wealth of new information regarding chromosomal changes in human cancer. Compilation and analysis of this data is essential if a clear picture of the incidence and specificity of cancer associated chromosome abnormalities is to be seen. This report provides an overview of our most recent and comprehensive analyses on chromosomal changes in 5345 neoplasms, providing further evidence for a clustering of chromosomal breakpoints in human neoplasia.
以有意义的方式吸收有关人类癌症染色体变化的大量新信息变得越来越困难。如果要清楚地了解与癌症相关的染色体异常的发生率和特异性，对这些数据进行汇编和分析至关重要。本报告概述了我们对5345例肿瘤染色体变化的最新综合分析，为人类肿瘤中染色体断点的聚集提供了进一步证据。
