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Influence of clonogenic assay methodology on measurement of drug sensitivities in vitro.

作者信息

Hepburn P J, Masters J R

出版信息

Cancer Chemother Pharmacol. 1986;16(1):80-2. doi: 10.1007/BF00255293.

Abstract

To assess the influence of clonogenic assay methodology on measurement of reproductive cell kill, the in vitro sensitivities of a human bladder cancer cell line, RT112, to methotrexate and adriamycin were determined using ten different procedures. Marked differences in dose-response to methotrexate, but not adriamycin, were observed.

摘要

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