Martins Jéssica Paula, Marson Fernando Augusto Lima
Laboratory of Molecular Biology and Genetics, São Francisco University, Bragança Paulista, SP, Brazil.
Laboratory of Clinical and Molecular Microbiology, São Francisco University, Bragança Paulista, SP, Brazil.
Heliyon. 2024 Sep 21;10(19):e38282. doi: 10.1016/j.heliyon.2024.e38282. eCollection 2024 Oct 15.
Chronic neuropathic pain arises from changes in the somatosensory nervous system and can lead to disability and intense physical and emotional suffering. Recognized as a painful syndrome, its causes are diverse, ranging from stroke, trauma, and diabetes mellitus to unknown origins. It tends to be more common in women, and it is estimated that the number of people affected by this condition increases every year as the population ages. Treatments are based on pharmacological and non-pharmacological interventions; however, the therapeutic plan does not always offer satisfactory relief, and learning to live with pain is, in most cases, the only option. The treatment aims to provide relief from symptoms, and alternative measures such as physiotherapy, physical exercise, and psychological support are strongly recommended. The coronavirus disease (COVID)-19 pandemic exacerbated the pain process, impacting quality of life, generating emotional problems, and potentially contributing to the increased incidence of neuropathic pain. In this context, the narrative review aimed to explore the complex panorama of chronic neuropathic pain, not only from a physiological perspective but also encompassing the psychological perspective and actions related to the pain process.
慢性神经性疼痛源于躯体感觉神经系统的变化,可导致残疾以及严重的身心痛苦。作为一种疼痛综合征,其病因多种多样,包括中风、创伤、糖尿病等,也有一些病因不明。这种疼痛在女性中更为常见,据估计,随着人口老龄化,每年受此疾病影响的人数都在增加。治疗方法基于药物和非药物干预;然而,治疗方案并不总是能带来令人满意的缓解效果,在大多数情况下,学会与疼痛共处是唯一的选择。治疗旨在缓解症状,强烈推荐采用物理治疗、体育锻炼和心理支持等替代措施。冠状病毒病(COVID)-19大流行加剧了疼痛过程,影响了生活质量,引发了情绪问题,并可能导致神经性疼痛发病率上升。在此背景下,本叙述性综述旨在探讨慢性神经性疼痛的复杂全貌,不仅从生理角度,还包括心理角度以及与疼痛过程相关的行为。