Department of Social Work, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.
School of Social Work, University of Illinois Urbana-Champaign, Champaign, Illinois, USA.
Gerontologist. 2024 Dec 1;64(12). doi: 10.1093/geront/gnae147.
Despite higher risks of developing Alzheimer's disease and Alzheimer's disease-related dementias among racial/ethnic minority populations, some maintain good cognition until old age. The aims of this study were to investigate heterogeneous cognitive trajectories among non-Hispanic Black and Hispanic older adults, examine cognitive impairment prevalence across trajectory classes, and identify associated social and behavioral determinants.
Using 11 waves of data from the Health and Retirement Study (1996-2016), 1,322 non-Hispanic Black and 747 Hispanic adults aged 50+ years in 1996 with normal cognition were included. Latent class growth modeling and multinomial logistic regressions were performed to examine cognitive trajectories and associated determinants.
For both racial/ethnic groups, 3 trajectory classes were identified: high, medium, and low cognition. In the low-cognition class, 87% and 100% of non-Hispanic Black and Hispanic participants, respectively, developed cognitive impairment. For both racial/ethnic groups, older age and living in rural areas during schooltime increased the likelihood of being in the low-cognition class, whereas more education was associated with a lower likelihood. Unique risk and protective determinants for non-Hispanic Black and Hispanic participants were also identified.
This study reveals the heterogeneity of cognitive trajectories among racial/ethnic minority older adults and various associated social and behavioral determinants. More prevention interventions and accessible, affordable diagnosis and treatment should be provided to older racial/ethnic minorities with these characteristics to reduce disparities. More research is needed to further explore associations between unique determinants and cognition in racial/ethnic minority populations to better inform interventions.
尽管少数族裔人群患阿尔茨海默病和与阿尔茨海默病相关的痴呆症的风险较高,但仍有一些人能够保持良好的认知能力直至老年。本研究旨在探讨非西班牙裔黑人和西班牙裔老年人认知轨迹的异质性,检验不同轨迹类别中的认知障碍发生率,并确定相关的社会和行为决定因素。
本研究使用健康与退休研究(Health and Retirement Study,HRS)1996-2016 年的 11 波数据,纳入了 1996 年年龄在 50 岁及以上、认知正常的 1322 名非西班牙裔黑人和 747 名西班牙裔成年人。采用潜在类别增长模型和多项逻辑回归分析来检验认知轨迹和相关决定因素。
对于两个种族/族裔群体,均识别出 3 个认知轨迹类别:高、中、低认知。在低认知类别中,分别有 87%和 100%的非西班牙裔黑人和西班牙裔参与者发展为认知障碍。对于两个种族/族裔群体,在校期间年龄较大和居住在农村地区会增加处于低认知类别的可能性,而受教育程度较高则与较低的可能性相关。还确定了非西班牙裔黑人和西班牙裔参与者特有的风险和保护决定因素。
本研究揭示了少数族裔老年人群认知轨迹的异质性以及各种相关的社会和行为决定因素。应该为具有这些特征的老年少数族裔提供更多的预防干预措施,以及可及且负担得起的诊断和治疗,以减少差异。需要进一步研究以进一步探讨少数族裔人群中独特决定因素与认知之间的关联,以为干预措施提供更好的信息。