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西澳大利亚先天性风疹综合征的减少:在校女生疫苗接种计划的影响?

The decline in congenital rubella syndrome in Western Australia: an impact of the school girl vaccination program?

作者信息

Stanley F J, Sim M, Wilson G, Worthington S

出版信息

Am J Public Health. 1986 Jan;76(1):35-7. doi: 10.2105/ajph.76.1.35.

Abstract

Rubella vaccination became available in 1970 in Australia. In Western Australia (WA), a school girl vaccination program was well established by 1971. Mothers under 26 years of age in 1983 would have been eligible for this program and they constitute 40 per cent of WA births. Data on Congenital Rubella Syndrome (CRS) cases were obtained for years of birth 1968-83 inclusive to ascertain if there had been an impact of the program on the CRS rate. Epidemics of rubella occurred in 1970-71, 1974, and 1979-80. The CRS rate has fallen steadily; it did not rise during the 1979-80 epidemic and was less than one in each year after 1977. All CRS cases born since 1974 were to mothers too old to have been eligible for the program. The data suggest that the vaccination program is effective, but this cannot be proven until data become available on pregnancy terminations.

摘要

风疹疫苗于1970年在澳大利亚上市。到1971年,西澳大利亚州(WA)已建立了完善的在校女生疫苗接种计划。1983年年龄在26岁以下的母亲符合该计划的条件,她们占西澳大利亚州新生儿的40%。获取了1968年至1983年(含)出生年份的先天性风疹综合征(CRS)病例数据,以确定该计划对CRS发病率是否有影响。风疹疫情发生在1970 - 1971年、1974年以及1979 - 1980年。CRS发病率稳步下降;在1979 - 1980年疫情期间没有上升,1977年之后每年发病率低于一例。1974年以来出生的所有CRS病例的母亲年龄都太大,不符合该计划的条件。数据表明疫苗接种计划是有效的,但在获得关于终止妊娠的数据之前无法得到证实。

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